Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   POF62_RS08570 Genome accession   NZ_CP116707
Coordinates   1673416..1674201 (-) Length   261 a.a.
NCBI ID   WP_001133184.1    Uniprot ID   Q3JZL4
Organism   Streptococcus agalactiae strain A909 sCas9revertant     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1668416..1679201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  POF62_RS08550 (POF62_08550) - 1670130..1670960 (-) 831 WP_000390093.1 pyruvate, water dikinase regulatory protein -
  POF62_RS08555 (POF62_08555) - 1670971..1671621 (-) 651 WP_071659924.1 helix-turn-helix transcriptional regulator -
  POF62_RS08560 (POF62_08560) - 1671774..1672754 (+) 981 WP_255297799.1 3-hydroxyacyl-CoA dehydrogenase -
  POF62_RS08565 (POF62_08565) - 1672801..1673349 (-) 549 WP_000158740.1 isochorismatase family cysteine hydrolase -
  POF62_RS08570 (POF62_08570) codY 1673416..1674201 (-) 786 WP_001133184.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  POF62_RS08575 (POF62_08575) - 1674327..1675538 (-) 1212 WP_000688108.1 pyridoxal phosphate-dependent aminotransferase -
  POF62_RS08580 (POF62_08580) - 1675805..1676257 (+) 453 WP_000080032.1 universal stress protein -
  POF62_RS08585 (POF62_08585) - 1676313..1677695 (-) 1383 WP_000974899.1 HAD-IIB family hydrolase -
  POF62_RS08590 (POF62_08590) - 1677764..1678726 (+) 963 WP_000723059.1 asparaginase domain-containing protein -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28971.10 Da        Isoelectric Point: 4.5011

>NTDB_id=711172 POF62_RS08570 WP_001133184.1 1673416..1674201(-) (codY) [Streptococcus agalactiae strain A909 sCas9revertant]
MPNLLEKTRKITSILQRSVDSLDAELPYNTMAAQLADIIDCNACIINGGGNLLGYAMKYKTNTNRVEEFFETKQFPDYYV
KSASRVYDTEANLSVDNDLSIFPVETKENFQDGITTIAPIYGGGMRLGTFIIWRNDKEFSDDDLILVEIASTVVGIQLLN
LQTENLEENIRKQTAVTMAINTLSYSEMKAVAAILGELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEYN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=711172 POF62_RS08570 WP_001133184.1 1673416..1674201(-) (codY) [Streptococcus agalactiae strain A909 sCas9revertant]
ATGCCGAATTTATTAGAAAAAACTAGAAAAATTACATCCATCTTACAGCGTTCCGTAGATAGCTTAGATGCCGAACTACC
ATATAATACAATGGCGGCTCAATTAGCTGATATTATTGACTGTAACGCATGTATTATTAATGGTGGTGGTAACTTACTTG
GCTATGCCATGAAATATAAAACAAACACTAACCGTGTGGAAGAATTTTTTGAAACAAAACAATTCCCAGATTACTATGTT
AAATCTGCTAGTCGTGTTTATGATACAGAAGCTAACTTATCAGTAGATAATGATTTGTCAATTTTCCCAGTTGAGACAAA
GGAAAACTTCCAAGATGGTATTACAACAATCGCTCCAATTTATGGTGGTGGAATGCGCTTGGGAACATTTATTATCTGGC
GTAATGATAAAGAATTTAGCGACGATGATTTGATTTTAGTTGAAATTGCAAGCACCGTTGTTGGTATTCAATTACTTAAC
CTTCAAACAGAAAATCTAGAAGAAAATATTCGTAAACAAACAGCGGTGACAATGGCTATCAACACTCTATCTTATTCAGA
AATGAAAGCTGTAGCTGCTATCTTAGGAGAATTAGATGGACTTGAAGGACGCCTAACGGCATCTGTTATTGCAGACCGTA
TTGGAATTACACGTTCCGTTATTGTAAATGCTCTTCGTAAATTGGAGTCTGCGGGAATCATTGAGAGCCGCTCACTCGGT
ATGAAGGGAACATACCTCAAAGTTATTAACGAAGGTATTTTTGACAAATTAAAAGAATATAATTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(201-261)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3JZL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

67.05

100

0.671
  codY Bacillus subtilis subsp. subtilis str. 168

51.417

94.636

0.487