Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J57_RS03940 Genome accession   NZ_AP018770
Coordinates   769326..770543 (+) Length   405 a.a.
NCBI ID   WP_014550481.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-II-7 isolate 13H35     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 764326..775543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J57_RS03920 (CHBNII7_07500) corC 765302..766201 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J57_RS03925 (CHBNII7_07510) ampD 766814..767374 (-) 561 WP_042599472.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J57_RS03930 (CHBNII7_07520) pilA 767489..767938 (+) 450 WP_042593498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J57_RS03935 (CHBNII7_07530) pilB 767935..769329 (+) 1395 WP_011271972.1 GspE/PulE family protein Machinery gene
  K6J57_RS03940 (CHBNII7_07540) pilC 769326..770543 (+) 1218 WP_014550481.1 type II secretion system F family protein Machinery gene
  K6J57_RS03945 (CHBNII7_07550) pilD 770540..771232 (+) 693 WP_014550482.1 A24 family peptidase Machinery gene
  K6J57_RS03950 (CHBNII7_07560) rho 771286..772548 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J57_RS03955 (CHBNII7_07570) metJ 772796..773113 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J57_RS03960 (CHBNII7_07580) cueR 773127..773513 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K6J57_RS03965 (CHBNII7_07590) - 773590..773796 (+) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  K6J57_RS03970 (CHBNII7_07600) - 773882..774088 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J57_RS03975 (CHBNII7_07610) - 774174..774380 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J57_RS03980 (CHBNII7_07620) - 774454..774660 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J57_RS03985 (CHBNII7_07630) - 774746..774952 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46089.34 Da        Isoelectric Point: 9.9010

>NTDB_id=70937 K6J57_RS03940 WP_014550481.1 769326..770543(+) (pilC) [Haemophilus influenzae strain CHBN-II-7 isolate 13H35]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=70937 K6J57_RS03940 WP_014550481.1 769326..770543(+) (pilC) [Haemophilus influenzae strain CHBN-II-7 isolate 13H35]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTACCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.983
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment