Detailed information NTG0070585

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FGCSD_RS06140
• Genome accession: NZ_AP018726
• Coordinates: 1215300..1216529 (-)
• Length: 409 a.a.
• NCBI ID: WP_003054192.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain Kdys0611
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1209047..1214579	1215300..1216529	flank	721

Gene organization within MGE regions

Location: 1209047..1216529

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGCSD_RS06115 (FGCSD_1157)	-	1209053..1210075 (+)	1023	WP_129555386.1	IS30 family transposase	-
FGCSD_RS06120 (FGCSD_1158)	clpC	1210485..1212584 (+)	2100	WP_129555799.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGCSD_RS06125 (FGCSD_1160)	-	1212641..1213383 (-)	743	Protein_1137	hypothetical protein	-
FGCSD_RS06130 (FGCSD_1161)	-	1213557..1214579 (+)	1023	WP_172595983.1	IS30 family transposase	-
FGCSD_RS06135 (FGCSD_1162)	yihA	1214691..1215290 (-)	600	WP_129555801.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FGCSD_RS06140 (FGCSD_1163)	clpX	1215300..1216529 (-)	1230	WP_003054192.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45060.54 Da
• Isoelectric Point: 4.5866

>NTDB_id=70585 FGCSD_RS06140 WP_003054192.1 1215300..1216529(-) (clpX) [Streptococcus dysgalactiae strain Kdys0611]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=70585 FGCSD_RS06140 WP_003054192.1 1215300..1216529(-) (clpX) [Streptococcus dysgalactiae strain Kdys0611]
ATGGCAGGAAATCGTACAAACGATATTAAAGTATATTGCTCATTTTGTGGTAAGAGCCAAGACGAAGTCAAAAAAATTAT
TGCAGGGAATAATGTTTTTATCTGTAATGAATGTGTGGCTTTGTCACAAGAAATTATTAAAGAAGAGTTAGCAGAAGAAG
TATTAGCTGACCTAACAGAAGTTCCAAAACCAAAAGAACTCCTTGAGGTTTTAAACCAGTATGTTGTTGGTCAAGATCGT
GCCAAACGTGCTTTATCAGTAGCTGTTTACAATCATTACAAACGCGTGTCATTCACGGAAAGTCGTGATGATGAAGATGT
TGAATTGCAAAAATCAAACATTTTAATGATTGGTCCAACAGGTTCAGGAAAGACTTTTCTCGCTCAAACCTTAGCTAAGA
GCTTAAATGTTCCTTTCGCGATTGCTGATGCAACCTCACTGACTGAAGCAGGTTATGTTGGAGAAGATGTGGAAAATATT
CTTCTCAAGCTTATCCAAGCAGCTGATTATAATGTGGAACGAGCAGAGCGTGGTATCATCTATGTCGATGAAATTGATAA
GATTGCTAAAAAAGGTGAAAATGTATCCATCACACGTGATGTTTCTGGTGAGGGAGTTCAACAGGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCTAGTGTTCCTCCTCAAGGTGGTCGTAAGCATCCAAATCAGGAAATGATTCAAATTGATACCAAA
AATATCTTGTTTATTGTTGGGGGAGCCTTTGACGGCATTGAAGACATTGTCAAACAACGTTTAGGAGAAAAAGTCATTGG
CTTTGGTCAAAACAGCCGAAAAATCGATGACAATGCTTCTTATATGCAAGAGATTATTTCAGAAGATATCCAAAAATTTG
GTCTTATCCCAGAGTTTATTGGACGCTTGCCAGTCGTAGCTGCTCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTAGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCAAATAAAGCCATTGAGCGTAAGACAGGCGCGCGTGGTCTTCGTTCTATTATCGAAGAAA
CAATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.487	100	0.895
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577