Detailed information NTG0705273

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NLY77_RS09085
• Genome accession: NZ_CP100431
• Coordinates: 1810816..1813053 (-)
• Length: 745 a.a.
• NCBI ID: WP_043033064.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1521251
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1805816..1818053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY77_RS09055 (NLY77_09055)	tmk	1805922..1806560 (-)	639	WP_002935358.1	dTMP kinase	-
NLY77_RS09060 (NLY77_09060)	-	1806735..1807601 (+)	867	WP_002935357.1	YitT family protein	-
NLY77_RS09065 (NLY77_09065)	-	1807638..1808909 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
NLY77_RS09070 (NLY77_09070)	-	1808915..1809742 (-)	828	WP_002935354.1	hypothetical protein	-
NLY77_RS09075 (NLY77_09075)	-	1809836..1810492 (-)	657	WP_002935353.1	CBS domain-containing protein	-
NLY77_RS09080 (NLY77_09080)	-	1810674..1810799 (-)	126	Protein_1770	IS982 family transposase	-
NLY77_RS09085 (NLY77_09085)	comEC/celB	1810816..1813053 (-)	2238	WP_043033064.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NLY77_RS09090 (NLY77_09090)	comEA/celA/cilE	1813037..1813699 (-)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
NLY77_RS09095 (NLY77_09095)	-	1813769..1814515 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NLY77_RS09100 (NLY77_09100)	-	1814661..1816106 (+)	1446	WP_013730320.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NLY77_RS09105 (NLY77_09105)	-	1816258..1817058 (+)	801	WP_013730319.1	ABC transporter ATP-binding protein	-
NLY77_RS09110 (NLY77_09110)	-	1817055..1817984 (+)	930	WP_009909659.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84157.32 Da
• Isoelectric Point: 8.1369

>NTDB_id=705273 NLY77_RS09085 WP_043033064.1 1810816..1813053(-) (comEC/celB) [Streptococcus suis strain 1521251]
MLRSIKLPCQPIHLALLAVAAYFVVRSFSLLTMGLLSLVLAVFGVRQGKAVFLRTLPLLALCGLFFGFQKLQWNRADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQELADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCFLLL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMIYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVLMEKIIVWVADLGLRPWILGKPSVVILILLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFMRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVHIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=705273 NLY77_RS09085 WP_043033064.1 1810816..1813053(-) (comEC/celB) [Streptococcus suis strain 1521251]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCGCTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGTGGTCTCTTTTTCGGATTTCAAAAGCTTCAATGGAATCGAGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTCCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTTTTTGTCTGTTTCTTGTTGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGATCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATTATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGTGGTAATTCTTATTCTCTTGCTGGTCTGTCTCTTCT
TACTTTATGATTTCCACAGAAAAAAGAAATGGCTCTTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGTGACAGCATCTTTATGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTTCTGACACACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCATATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATTAATGTGCCTGTCCATGTGGTCAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.24	99.732	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.414	100	0.536
comEC/celB	Streptococcus pneumoniae TIGR4	52.463	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae D39	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae R6	52.197	100	0.526
comEC	Lactococcus lactis subsp. cremoris KW2	49.332	100	0.495