Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   NLY77_RS06445 Genome accession   NZ_CP100431
Coordinates   1265986..1266825 (-) Length   279 a.a.
NCBI ID   WP_029174677.1    Uniprot ID   A0A0M9FKY2
Organism   Streptococcus suis strain 1521251     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1260986..1271825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS06430 (NLY77_06430) uidA 1261346..1263145 (-) 1800 WP_029174680.1 beta-glucuronidase -
  NLY77_RS06435 (NLY77_06435) - 1263161..1264189 (-) 1029 WP_024403160.1 sugar kinase -
  NLY77_RS06440 (NLY77_06440) - 1264246..1265799 (-) 1554 WP_024394170.1 MFS transporter -
  NLY77_RS06445 (NLY77_06445) endA 1265986..1266825 (-) 840 WP_029174677.1 DNA/RNA non-specific endonuclease Machinery gene
  NLY77_RS06450 (NLY77_06450) - 1266855..1267046 (-) 192 WP_012775177.1 DNA-directed RNA polymerase subunit beta -
  NLY77_RS06455 (NLY77_06455) murA 1267039..1268322 (-) 1284 Protein_1248 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  NLY77_RS06460 (NLY77_06460) - 1268347..1268571 (-) 225 WP_012775178.1 DUF1146 family protein -
  NLY77_RS06465 (NLY77_06465) - 1268631..1269047 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  NLY77_RS06470 (NLY77_06470) atpD 1269057..1270463 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  NLY77_RS06475 (NLY77_06475) - 1270483..1271361 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30159.40 Da        Isoelectric Point: 6.2370

>NTDB_id=705261 NLY77_RS06445 WP_029174677.1 1265986..1266825(-) (endA) [Streptococcus suis strain 1521251]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREEIGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFIPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=705261 NLY77_RS06445 WP_029174677.1 1265986..1266825(-) (endA) [Streptococcus suis strain 1521251]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGTTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACGGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGACCGTGAAG
AAATAGGAAATGGTCGGACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCTTAGAGTTCAATGTGTTCATTCCAAATGTGCAGAGTGGTCTCAG
TATCAATTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FKY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.492

84.588

0.588
  endA Streptococcus pneumoniae D39

69.492

84.588

0.588
  endA Streptococcus pneumoniae R6

69.492

84.588

0.588
  endA Streptococcus pneumoniae TIGR4

69.492

84.588

0.588