Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   NKZ66_RS06095 Genome accession   NZ_CP100336
Coordinates   1214961..1215623 (-) Length   220 a.a.
NCBI ID   WP_079394055.1    Uniprot ID   A0A0Z8ST93
Organism   Streptococcus suis strain STC81     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209961..1220623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ66_RS06075 (NKZ66_06075) - 1210850..1211677 (-) 828 WP_024417275.1 hypothetical protein -
  NKZ66_RS06080 (NKZ66_06080) - 1211770..1212426 (-) 657 WP_023370708.1 CBS domain-containing protein -
  NKZ66_RS06085 (NKZ66_06085) - 1212609..1212731 (-) 123 Protein_1152 IS982 family transposase -
  NKZ66_RS06090 (NKZ66_06090) comEC/celB 1212740..1214977 (-) 2238 WP_044752722.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NKZ66_RS06095 (NKZ66_06095) comEA/celA/cilE 1214961..1215623 (-) 663 WP_079394055.1 helix-hairpin-helix domain-containing protein Machinery gene
  NKZ66_RS06100 (NKZ66_06100) - 1215693..1216439 (-) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NKZ66_RS06105 (NKZ66_06105) - 1216586..1218031 (+) 1446 WP_172001200.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  NKZ66_RS06110 (NKZ66_06110) - 1218183..1218983 (+) 801 WP_172001201.1 ABC transporter ATP-binding protein -
  NKZ66_RS06115 (NKZ66_06115) - 1218980..1219909 (+) 930 WP_172001202.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23368.04 Da        Isoelectric Point: 4.0751

>NTDB_id=704556 NKZ66_RS06095 WP_079394055.1 1214961..1215623(-) (comEA/celA/cilE) [Streptococcus suis strain STC81]
MDTMKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTAQTSSSSDLVEETSTEVSEEPSQLVVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTNASSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=704556 NKZ66_RS06095 WP_079394055.1 1214961..1215623(-) (comEA/celA/cilE) [Streptococcus suis strain STC81]
ATGGATACGATGAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCTGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGCCAACCAGCAAAGTCTGACCAGACAGGCCTGACAGACTTTCCACAGACCGCACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAACCCAGTCAGCTAGTCGTTGATGTCAAA
GGAGCGGTGGAAAAACCAGGGCTCTACACCTTAGAAGCTGGTGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCAAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGAATGCCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTTTCGGGCATTGGCGACAAGACTATGGAAAGCATTC
GACCTTATGTTACGGTCGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8ST93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.649

100

0.491
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.43

100

0.491
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.43

100

0.491
  comEA/celA/cilE Streptococcus pneumoniae D39

48.43

100

0.491
  comEA/celA/cilE Streptococcus pneumoniae R6

48.43

100

0.491
  comEA/celA/cilE Streptococcus mitis SK321

46.847

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

37.391

100

0.391