Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H7675_RS00670 Genome accession   NZ_AP023389
Coordinates   104269..104553 (+) Length   94 a.a.
NCBI ID   WP_011284422.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain KUN-0012590     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99269..109553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7675_RS00645 (KUN2590_00810) - 101215..101580 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7675_RS00650 (KUN2590_00820) comGA 101673..102611 (+) 939 WP_184004775.1 competence type IV pilus ATPase ComGA Machinery gene
  H7675_RS00655 (KUN2590_00830) comGB 102547..103581 (+) 1035 WP_232087598.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7675_RS00660 (KUN2590_00840) comGC 103583..103909 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7675_RS00665 (KUN2590_00850) comGD 103884..104312 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7675_RS00670 (KUN2590_00860) comGE 104269..104553 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7675_RS00675 (KUN2590_00870) comGF 104546..104980 (+) 435 WP_111711329.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7675_RS00680 (KUN2590_00880) comGG 104964..105290 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7675_RS00685 (KUN2590_00890) comGH 105388..106341 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7675_RS00690 (KUN2590_00900) - 106400..107596 (+) 1197 WP_111711330.1 acetate kinase -
  H7675_RS00695 (KUN2590_00910) - 107783..108091 (+) 309 WP_011284425.1 hypothetical protein -
  H7675_RS00700 (KUN2590_00920) proC 108174..108944 (-) 771 WP_011284426.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10654.59 Da        Isoelectric Point: 8.9043

>NTDB_id=70423 H7675_RS00670 WP_011284422.1 104269..104553(+) (comGE) [Streptococcus pyogenes strain KUN-0012590]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEITLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=70423 H7675_RS00670 WP_011284422.1 104269..104553(+) (comGE) [Streptococcus pyogenes strain KUN-0012590]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGTAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATAACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383