Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   NHM99_RS18465 Genome accession   NZ_CP099801
Coordinates   3583670..3584449 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus paranthracis strain SSBC101     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3557048..3603082 3583670..3584449 within 0


Gene organization within MGE regions


Location: 3557048..3603082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHM99_RS18345 (NHM99_18345) - 3557242..3557493 (-) 252 WP_001239754.1 YlmC/YmxH family sporulation protein -
  NHM99_RS18350 (NHM99_18350) - 3557620..3558861 (-) 1242 WP_000592994.1 pitrilysin family protein -
  NHM99_RS18355 (NHM99_18355) - 3558948..3559848 (-) 901 Protein_3565 polysaccharide deacetylase family protein -
  NHM99_RS18360 (NHM99_18360) pnp 3560000..3562137 (-) 2138 Protein_3566 polyribonucleotide nucleotidyltransferase -
  NHM99_RS18365 (NHM99_18365) rpsO 3562298..3562567 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  NHM99_RS18370 (NHM99_18370) ribF 3562668..3563639 (-) 972 WP_000766710.1 bifunctional riboflavin kinase/FAD synthetase -
  NHM99_RS18375 (NHM99_18375) truB 3563683..3564606 (-) 924 WP_000399344.1 tRNA pseudouridine(55) synthase TruB -
  NHM99_RS18380 (NHM99_18380) rbfA 3564693..3565049 (-) 357 WP_000776440.1 30S ribosome-binding factor RbfA -
  NHM99_RS18385 (NHM99_18385) - 3565065..3565346 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  NHM99_RS18390 (NHM99_18390) infB 3565343..3567403 (-) 2061 WP_000036342.1 translation initiation factor IF-2 -
  NHM99_RS18395 (NHM99_18395) - 3567408..3567719 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  NHM99_RS18400 (NHM99_18400) rnpM 3567720..3567992 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  NHM99_RS18405 (NHM99_18405) nusA 3568004..3569110 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  NHM99_RS18410 (NHM99_18410) rimP 3569128..3569598 (-) 471 WP_253129555.1 ribosome maturation factor RimP -
  NHM99_RS18415 (NHM99_18415) - 3569931..3574232 (-) 4302 WP_000059980.1 PolC-type DNA polymerase III -
  NHM99_RS18420 (NHM99_18420) - 3574357..3576057 (-) 1701 WP_000814305.1 proline--tRNA ligase -
  NHM99_RS18425 (NHM99_18425) rseP 3576167..3577423 (-) 1257 WP_001090248.1 RIP metalloprotease RseP -
  NHM99_RS18430 (NHM99_18430) dxr 3577440..3578582 (-) 1143 WP_000790362.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  NHM99_RS18435 (NHM99_18435) cdsA 3578606..3579397 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  NHM99_RS18440 (NHM99_18440) uppS 3579415..3580191 (-) 777 WP_000971301.1 isoprenyl transferase -
  NHM99_RS18445 (NHM99_18445) frr 3580277..3580834 (-) 558 WP_000531500.1 ribosome recycling factor -
  NHM99_RS18450 (NHM99_18450) pyrH 3580837..3581559 (-) 723 WP_000042663.1 UMP kinase -
  NHM99_RS18455 (NHM99_18455) tsf 3581626..3582513 (-) 888 WP_014297954.1 translation elongation factor Ts -
  NHM99_RS18460 (NHM99_18460) rpsB 3582617..3583318 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  NHM99_RS18465 (NHM99_18465) codY 3583670..3584449 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  NHM99_RS18470 (NHM99_18470) hslU 3584527..3585918 (-) 1392 WP_000550081.1 ATP-dependent protease ATPase subunit HslU -
  NHM99_RS18475 (NHM99_18475) hslV 3585941..3586483 (-) 543 WP_000526271.1 ATP-dependent protease proteolytic subunit HslV -
  NHM99_RS18480 (NHM99_18480) xerC 3586526..3587425 (-) 900 WP_001101229.1 tyrosine recombinase XerC -
  NHM99_RS18485 (NHM99_18485) trmFO 3587491..3588795 (-) 1305 WP_002028254.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  NHM99_RS18490 (NHM99_18490) topA 3588846..3590924 (-) 2079 WP_001286973.1 type I DNA topoisomerase -
  NHM99_RS18495 (NHM99_18495) dprA 3591069..3591938 (-) 870 WP_000818031.1 DNA-processing protein DprA -
  NHM99_RS18500 (NHM99_18500) sucD 3592026..3592928 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  NHM99_RS18505 (NHM99_18505) sucC 3592948..3594108 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  NHM99_RS18510 (NHM99_18510) rnhB 3594302..3595075 (-) 774 WP_001174725.1 ribonuclease HII -
  NHM99_RS18515 (NHM99_18515) ylqF 3595127..3596017 (-) 891 WP_000236700.1 ribosome biogenesis GTPase YlqF -
  NHM99_RS18520 (NHM99_18520) lepB 3596038..3596589 (-) 552 WP_000711857.1 signal peptidase I -
  NHM99_RS18525 (NHM99_18525) rplS 3596691..3597035 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  NHM99_RS18530 (NHM99_18530) trmD 3597181..3597915 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  NHM99_RS18535 (NHM99_18535) rimM 3597915..3598430 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  NHM99_RS18540 (NHM99_18540) - 3598554..3598781 (-) 228 WP_000737403.1 KH domain-containing protein -
  NHM99_RS18545 (NHM99_18545) rpsP 3598796..3599068 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  NHM99_RS18550 (NHM99_18550) ffh 3599169..3600518 (-) 1350 WP_000863461.1 signal recognition particle protein -
  NHM99_RS18555 (NHM99_18555) - 3600531..3600863 (-) 333 WP_000891062.1 putative DNA-binding protein -
  NHM99_RS18560 (NHM99_18560) ftsY 3600997..3601985 (-) 989 Protein_3606 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=701696 NHM99_RS18465 WP_000421288.1 3583670..3584449(-) (codY) [Bacillus paranthracis strain SSBC101]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=701696 NHM99_RS18465 WP_000421288.1 3583670..3584449(-) (codY) [Bacillus paranthracis strain SSBC101]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGCTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATTGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTACTAAACGACAAATTCTTACATGAACTTGCTAAATTGAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459