Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | NDQ66_RS02670 | Genome accession | NZ_CP098532 |
| Coordinates | 517216..517878 (+) | Length | 220 a.a. |
| NCBI ID | WP_041421240.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 10537 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 515556..559257 | 517216..517878 | within | 0 |
Gene organization within MGE regions
Location: 515556..559257
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDQ66_RS02665 (NDQ66_02645) | dnaB | 515556..516959 (+) | 1404 | WP_012503477.1 | replicative DNA helicase | - |
| NDQ66_RS12085 | - | 516953..517065 (-) | 113 | Protein_519 | IS5/IS1182 family transposase | - |
| NDQ66_RS02670 (NDQ66_02650) | pilH | 517216..517878 (+) | 663 | WP_041421240.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NDQ66_RS02675 (NDQ66_02655) | pilI | 517910..518524 (+) | 615 | WP_012503479.1 | type IV pilus modification protein PilV | Machinery gene |
| NDQ66_RS02680 (NDQ66_02660) | pilJ | 518521..519480 (+) | 960 | WP_260247272.1 | PilW family protein | Machinery gene |
| NDQ66_RS02685 (NDQ66_02665) | pilK | 519459..520058 (+) | 600 | WP_260247273.1 | pilus assembly protein | Machinery gene |
| NDQ66_RS02690 (NDQ66_02670) | pilL | 520073..520546 (+) | 474 | WP_012503482.1 | PilX family type IV pilin | Machinery gene |
| NDQ66_RS02695 (NDQ66_02675) | - | 520616..520924 (-) | 309 | WP_003706588.1 | AzlD family protein | - |
| NDQ66_RS02700 (NDQ66_02680) | - | 520921..521632 (-) | 712 | Protein_526 | AzlC family ABC transporter permease | - |
| NDQ66_RS02705 (NDQ66_02685) | dut | 521798..522250 (+) | 453 | WP_003701071.1 | dUTP diphosphatase | - |
| NDQ66_RS02710 (NDQ66_02690) | dapC | 522322..523509 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| NDQ66_RS02715 (NDQ66_02695) | yaaA | 523665..524444 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| NDQ66_RS02730 (NDQ66_02710) | - | 524974..526175 (+) | 1202 | Protein_530 | tyrosine-type recombinase/integrase | - |
| NDQ66_RS02735 (NDQ66_02715) | - | 526531..526800 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| NDQ66_RS02740 (NDQ66_02720) | - | 526995..527678 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| NDQ66_RS11915 | - | 527959..528225 (-) | 267 | Protein_533 | hypothetical protein | - |
| NDQ66_RS02750 (NDQ66_02730) | - | 528336..528551 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NDQ66_RS02755 (NDQ66_02735) | - | 528603..529094 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| NDQ66_RS02760 (NDQ66_02740) | - | 529091..529273 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NDQ66_RS02765 (NDQ66_02745) | - | 529413..530099 (-) | 687 | WP_012503754.1 | phage replication initiation protein, NGO0469 family | - |
| NDQ66_RS02770 (NDQ66_02750) | - | 530168..530329 (-) | 162 | WP_003702497.1 | hypothetical protein | - |
| NDQ66_RS02775 (NDQ66_02755) | - | 530326..530604 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| NDQ66_RS02780 (NDQ66_02760) | - | 530757..531089 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| NDQ66_RS02785 (NDQ66_02765) | - | 531230..531517 (-) | 288 | WP_071236956.1 | hypothetical protein | - |
| NDQ66_RS02790 (NDQ66_02770) | - | 531514..531990 (-) | 477 | WP_012504141.1 | DUF6948 domain-containing protein | - |
| NDQ66_RS02795 (NDQ66_02775) | - | 532023..532223 (-) | 201 | WP_003704298.1 | hypothetical protein | - |
| NDQ66_RS02800 (NDQ66_02780) | - | 532422..532835 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| NDQ66_RS02805 (NDQ66_02785) | - | 532832..533293 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| NDQ66_RS02810 (NDQ66_02790) | - | 533310..533747 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| NDQ66_RS02815 (NDQ66_02795) | - | 533862..534578 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| NDQ66_RS02820 (NDQ66_02800) | - | 534653..534883 (+) | 231 | WP_020997318.1 | Cro/CI family transcriptional regulator | - |
| NDQ66_RS02825 (NDQ66_02805) | - | 534963..535118 (+) | 156 | WP_003691446.1 | hypothetical protein | - |
| NDQ66_RS02830 (NDQ66_02810) | - | 535095..535283 (-) | 189 | WP_003698903.1 | hypothetical protein | - |
| NDQ66_RS02835 (NDQ66_02815) | - | 535456..535683 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDQ66_RS02840 (NDQ66_02820) | - | 535680..535817 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| NDQ66_RS02845 (NDQ66_02825) | - | 536362..536865 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| NDQ66_RS02850 (NDQ66_02830) | - | 536862..538223 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDQ66_RS02855 (NDQ66_02835) | - | 538240..538470 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NDQ66_RS02860 (NDQ66_02840) | - | 538562..539056 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| NDQ66_RS02865 (NDQ66_02845) | - | 539253..539402 (+) | 150 | WP_012503493.1 | hypothetical protein | - |
| NDQ66_RS02870 (NDQ66_02850) | - | 539431..539712 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDQ66_RS02875 (NDQ66_02855) | - | 539703..540140 (+) | 438 | WP_041421250.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDQ66_RS02880 (NDQ66_02860) | - | 540133..540438 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| NDQ66_RS02885 (NDQ66_02865) | - | 540435..540818 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| NDQ66_RS02890 (NDQ66_02870) | - | 540809..541327 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| NDQ66_RS02895 (NDQ66_02875) | - | 541392..541814 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| NDQ66_RS02900 (NDQ66_02880) | - | 541814..542353 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| NDQ66_RS02905 (NDQ66_02885) | - | 542334..543608 (+) | 1275 | WP_003701186.1 | PBSX family phage terminase large subunit | - |
| NDQ66_RS02910 (NDQ66_02890) | - | 543593..545860 (+) | 2268 | WP_228369784.1 | hypothetical protein | - |
| NDQ66_RS02915 (NDQ66_02895) | - | 546097..547293 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| NDQ66_RS02920 (NDQ66_02900) | - | 547290..548504 (+) | 1215 | WP_044270986.1 | hypothetical protein | - |
| NDQ66_RS12090 | - | 548707..554616 (+) | 5910 | WP_033909227.1 | PLxRFG domain-containing protein | - |
| NDQ66_RS02935 (NDQ66_02915) | - | 555242..556528 (+) | 1287 | WP_071200297.1 | DUF4043 family protein | - |
| NDQ66_RS02940 (NDQ66_02920) | - | 556583..557056 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| NDQ66_RS02945 (NDQ66_02925) | - | 557062..557547 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| NDQ66_RS02950 (NDQ66_02930) | - | 557544..557819 (+) | 276 | WP_010358526.1 | hypothetical protein | - |
| NDQ66_RS02955 (NDQ66_02935) | - | 557810..558217 (+) | 408 | WP_010358525.1 | hypothetical protein | - |
| NDQ66_RS02960 (NDQ66_02940) | - | 558208..558369 (+) | 162 | WP_003687999.1 | hypothetical protein | - |
| NDQ66_RS02965 (NDQ66_02945) | - | 558406..559257 (-) | 852 | WP_260247274.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 220 a.a. Molecular weight: 24496.91 Da Isoelectric Point: 9.6166
>NTDB_id=696630 NDQ66_RS02670 WP_041421240.1 517216..517878(+) (pilH) [Neisseria gonorrhoeae strain 10537]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
Nucleotide
Download Length: 663 bp
>NTDB_id=696630 NDQ66_RS02670 WP_041421240.1 517216..517878(+) (pilH) [Neisseria gonorrhoeae strain 10537]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
95.909 |
100 |
0.959 |