Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | NC848_RS02345 | Genome accession | NZ_CP098460 |
| Coordinates | 451539..452204 (+) | Length | 221 a.a. |
| NCBI ID | WP_003699624.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 10814 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 440056..506845 | 451539..452204 | within | 0 |
Gene organization within MGE regions
Location: 440056..506845
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NC848_RS02290 (NC848_02275) | - | 440056..441039 (+) | 984 | WP_003687900.1 | ribose-phosphate pyrophosphokinase | - |
| NC848_RS02295 (NC848_02280) | - | 441106..441678 (+) | 573 | WP_003687901.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| NC848_RS02300 (NC848_02285) | - | 441804..442973 (-) | 1170 | WP_003687902.1 | D-alanyl-D-alanine carboxypeptidase family protein | - |
| NC848_RS02305 (NC848_02290) | ilvA | 443122..444648 (+) | 1527 | WP_003687904.1 | threonine ammonia-lyase, biosynthetic | - |
| NC848_RS02310 (NC848_02295) | - | 444704..445780 (-) | 1077 | WP_003692814.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| NC848_RS02315 (NC848_02300) | cysW | 445777..446637 (-) | 861 | WP_003699617.1 | sulfate ABC transporter permease subunit CysW | - |
| NC848_RS02320 (NC848_02305) | cysT | 446826..447653 (-) | 828 | WP_003699619.1 | sulfate ABC transporter permease subunit CysT | - |
| NC848_RS02325 (NC848_02310) | - | 447834..448166 (+) | 333 | WP_003687908.1 | hypothetical protein | - |
| NC848_RS02330 (NC848_02315) | - | 448493..449002 (+) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| NC848_RS02335 (NC848_02320) | - | 449234..449815 (-) | 582 | WP_003690895.1 | superoxide dismutase | - |
| NC848_RS02340 (NC848_02325) | dnaB | 449979..451385 (+) | 1407 | WP_003699622.1 | replicative DNA helicase | - |
| NC848_RS02345 (NC848_02330) | pilH | 451539..452204 (+) | 666 | WP_003699624.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NC848_RS02350 (NC848_02335) | pilV | 452236..452847 (+) | 612 | WP_260240068.1 | type IV pilus modification protein PilV | Machinery gene |
| NC848_RS02355 (NC848_02340) | pilJ | 452844..453785 (+) | 942 | WP_047920195.1 | PilW family protein | Machinery gene |
| NC848_RS02360 (NC848_02345) | pilK | 453764..454375 (+) | 612 | WP_033911077.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| NC848_RS02365 (NC848_02350) | pilL | 454377..454850 (+) | 474 | WP_172760650.1 | PilX family type IV pilin | Machinery gene |
| NC848_RS02370 (NC848_02355) | - | 454920..455228 (-) | 309 | WP_025456177.1 | AzlD family protein | - |
| NC848_RS02375 (NC848_02360) | - | 455225..455935 (-) | 711 | Protein_465 | AzlC family ABC transporter permease | - |
| NC848_RS02380 (NC848_02365) | dut | 456101..456553 (+) | 453 | WP_003699637.1 | dUTP diphosphatase | - |
| NC848_RS02385 (NC848_02370) | dapC | 456629..457816 (+) | 1188 | WP_003699639.1 | succinyldiaminopimelate transaminase | - |
| NC848_RS02390 (NC848_02375) | yaaA | 457972..458751 (+) | 780 | WP_003699641.1 | peroxide stress protein YaaA | - |
| NC848_RS02405 (NC848_02390) | - | 459281..460474 (+) | 1194 | WP_017146746.1 | integrase arm-type DNA-binding domain-containing protein | - |
| NC848_RS02410 (NC848_02395) | - | 460830..461099 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| NC848_RS02415 (NC848_02400) | - | 461294..461977 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| NC848_RS11725 | - | 462258..462524 (-) | 267 | Protein_472 | hypothetical protein | - |
| NC848_RS02425 (NC848_02410) | - | 462635..462850 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NC848_RS02430 (NC848_02415) | - | 462902..463393 (-) | 492 | WP_033911206.1 | siphovirus Gp157 family protein | - |
| NC848_RS02435 (NC848_02420) | - | 463390..463572 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NC848_RS02440 (NC848_02425) | - | 463712..464398 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| NC848_RS02445 (NC848_02430) | - | 464467..464628 (-) | 162 | WP_003693867.1 | hypothetical protein | - |
| NC848_RS02450 (NC848_02435) | - | 464625..464903 (-) | 279 | WP_041421244.1 | NGO1622 family putative holin | - |
| NC848_RS02455 (NC848_02440) | - | 465056..465388 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| NC848_RS02460 (NC848_02445) | - | 465530..465835 (-) | 306 | WP_260240049.1 | hypothetical protein | - |
| NC848_RS02465 (NC848_02450) | - | 465832..466308 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| NC848_RS02470 (NC848_02455) | - | 466341..466541 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| NC848_RS02475 (NC848_02460) | - | 466739..467152 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| NC848_RS02480 (NC848_02465) | - | 467149..467610 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| NC848_RS02485 (NC848_02470) | - | 467627..468064 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| NC848_RS02490 (NC848_02475) | - | 468177..468893 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| NC848_RS02495 (NC848_02480) | - | 468968..469198 (+) | 231 | WP_020997318.1 | Cro/CI family transcriptional regulator | - |
| NC848_RS02500 (NC848_02485) | - | 469278..469433 (+) | 156 | WP_003698902.1 | hypothetical protein | - |
| NC848_RS02505 (NC848_02490) | - | 469410..469598 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| NC848_RS02510 (NC848_02495) | - | 469771..469998 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NC848_RS02515 (NC848_02500) | - | 470116..471180 (+) | 1065 | WP_003689134.1 | hypothetical protein | - |
| NC848_RS02520 (NC848_02505) | - | 471177..472538 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NC848_RS02525 (NC848_02510) | - | 472555..472785 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NC848_RS02530 (NC848_02515) | - | 472877..473371 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NC848_RS02535 (NC848_02520) | - | 473548..473697 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| NC848_RS02540 (NC848_02525) | - | 473725..474006 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NC848_RS02545 (NC848_02530) | - | 473997..474377 (+) | 381 | WP_033911195.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NC848_RS02550 | - | 474394..474522 (-) | 129 | WP_012503747.1 | hypothetical protein | - |
| NC848_RS02555 (NC848_02535) | - | 474644..475051 (+) | 408 | WP_003691430.1 | hypothetical protein | - |
| NC848_RS02560 (NC848_02540) | - | 475142..476302 (+) | 1161 | WP_003691428.1 | type I restriction endonuclease | - |
| NC848_RS02565 (NC848_02545) | - | 476584..477453 (+) | 870 | WP_003700071.1 | BRO family protein | - |
| NC848_RS02570 (NC848_02550) | - | 477746..478195 (+) | 450 | WP_003689093.1 | hypothetical protein | - |
| NC848_RS02575 (NC848_02555) | terL | 478257..479678 (+) | 1422 | WP_003697216.1 | phage terminase large subunit | - |
| NC848_RS02580 (NC848_02560) | - | 479675..481822 (+) | 2148 | WP_003691423.1 | phage portal protein | - |
| NC848_RS02585 (NC848_02565) | - | 481890..483047 (+) | 1158 | WP_003700068.1 | hypothetical protein | - |
| NC848_RS02590 (NC848_02570) | - | 483088..484587 (+) | 1500 | WP_003691419.1 | hypothetical protein | - |
| NC848_RS02595 (NC848_02575) | - | 484594..484956 (+) | 363 | WP_003689082.1 | hypothetical protein | - |
| NC848_RS02600 (NC848_02580) | - | 484959..485489 (+) | 531 | WP_003689080.1 | head-tail connector protein | - |
| NC848_RS02605 (NC848_02585) | - | 485489..485971 (+) | 483 | WP_003706029.1 | HK97 gp10 family phage protein | - |
| NC848_RS02610 (NC848_02590) | - | 485968..486396 (+) | 429 | WP_003697213.1 | hypothetical protein | - |
| NC848_RS02615 (NC848_02595) | - | 486422..487195 (+) | 774 | WP_003691416.1 | hypothetical protein | - |
| NC848_RS02620 (NC848_02600) | - | 487257..487586 (+) | 330 | WP_003689072.1 | hypothetical protein | - |
| NC848_RS02625 (NC848_02605) | - | 487598..487864 (+) | 267 | WP_003692873.1 | hypothetical protein | - |
| NC848_RS02630 (NC848_02610) | - | 487864..488463 (+) | 600 | WP_003692874.1 | DUF2460 domain-containing protein | - |
| NC848_RS02635 (NC848_02615) | - | 488460..489314 (+) | 855 | WP_003698614.1 | DUF2163 domain-containing protein | - |
| NC848_RS02640 (NC848_02620) | - | 489316..489747 (+) | 432 | WP_003689064.1 | NlpC/P60 family protein | - |
| NC848_RS02645 (NC848_02625) | - | 489775..490053 (-) | 279 | WP_229930233.1 | helix-turn-helix domain-containing protein | - |
| NC848_RS02650 (NC848_02630) | - | 490293..494438 (+) | 4146 | WP_025456199.1 | phage tail protein | - |
| NC848_RS02655 (NC848_02635) | - | 494550..494855 (+) | 306 | WP_003689058.1 | hypothetical protein | - |
| NC848_RS02660 (NC848_02640) | - | 494926..495396 (+) | 471 | WP_025455988.1 | hypothetical protein | - |
| NC848_RS02665 (NC848_02645) | - | 495397..495729 (+) | 333 | WP_003691408.1 | hypothetical protein | - |
| NC848_RS02670 (NC848_02650) | - | 496097..496444 (-) | 348 | WP_003689051.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NC848_RS02675 (NC848_02655) | - | 496444..496680 (-) | 237 | WP_003689049.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| NC848_RS02680 (NC848_02660) | - | 496887..497426 (+) | 540 | WP_047951643.1 | TIGR02594 family protein | - |
| NC848_RS02685 (NC848_02665) | - | 497426..497584 (+) | 159 | WP_003691816.1 | hypothetical protein | - |
| NC848_RS02690 (NC848_02670) | - | 497568..497909 (+) | 342 | WP_003700102.1 | hypothetical protein | - |
| NC848_RS02695 (NC848_02675) | - | 497893..498066 (+) | 174 | WP_012504144.1 | hypothetical protein | - |
| NC848_RS02700 (NC848_02680) | - | 498378..498527 (+) | 150 | WP_003691402.1 | hypothetical protein | - |
| NC848_RS02705 (NC848_02685) | - | 498557..501601 (+) | 3045 | WP_229930235.1 | tape measure protein | - |
| NC848_RS02710 (NC848_02690) | - | 501661..502140 (-) | 480 | WP_002241413.1 | DUF4760 domain-containing protein | - |
| NC848_RS02715 (NC848_02695) | - | 502482..503471 (-) | 990 | WP_003689040.1 | site-specific integrase | - |
| NC848_RS02720 (NC848_02700) | - | 503731..503919 (-) | 189 | WP_003689039.1 | hypothetical protein | - |
| NC848_RS02725 (NC848_02705) | purM | 504160..505194 (+) | 1035 | WP_003692893.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| NC848_RS02730 (NC848_02710) | - | 506192..506845 (+) | 654 | WP_134994130.1 | IS1595 family transposase | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24648.03 Da Isoelectric Point: 8.8981
>NTDB_id=695675 NC848_RS02345 WP_003699624.1 451539..452204(+) (pilH) [Neisseria gonorrhoeae strain 10814]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NRCDFSKKGWGMLAFGDKNGNKAYDGDVADVFLRSVVLNDDINDKRIDYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTT
DQHLTERSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRAVCQH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPVQVKKDGAPN
NRCDFSKKGWGMLAFGDKNGNKAYDGDVADVFLRSVVLNDDINDKRIDYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTT
DQHLTERSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRAVCQH
Nucleotide
Download Length: 666 bp
>NTDB_id=695675 NC848_RS02345 WP_003699624.1 451539..452204(+) (pilH) [Neisseria gonorrhoeae strain 10814]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGCATATGACGGCGA
TGTGGCGGATGTTTTCCTCCGCAGCGTGGTATTGAATGATGATATCAATGATAAGCGGATTGATTATGCCTTCAACCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACGTTCAATCAAAACGGGACGTTCGGTTATACGACA
GACCAGCATCTTACAGAGCGATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGCCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGCATATGACGGCGA
TGTGGCGGATGTTTTCCTCCGCAGCGTGGTATTGAATGATGATATCAATGATAAGCGGATTGATTATGCCTTCAACCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACGTTCAATCAAAACGGGACGTTCGGTTATACGACA
GACCAGCATCTTACAGAGCGATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
90.045 |
100 |
0.9 |