Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SR187_RS03495 Genome accession   NZ_AP018400
Coordinates   716438..717280 (+) Length   280 a.a.
NCBI ID   WP_120171529.1    Uniprot ID   A0A2Z5TPR3
Organism   Streptococcus ruminantium strain GUT-187     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 711438..722280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS03465 (SR187_3545) - 711646..712524 (+) 879 WP_024532405.1 F0F1 ATP synthase subunit gamma -
  SR187_RS03470 (SR187_3550) atpD 712696..714102 (+) 1407 WP_024532406.1 F0F1 ATP synthase subunit beta -
  SR187_RS03475 (SR187_3555) - 714112..714528 (+) 417 WP_120171525.1 F0F1 ATP synthase subunit epsilon -
  SR187_RS03480 (SR187_3560) - 714692..714919 (+) 228 WP_120171526.1 DUF1146 family protein -
  SR187_RS03485 (SR187_3565) murA 714941..716224 (+) 1284 WP_120171527.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SR187_RS03490 (SR187_3570) - 716217..716408 (+) 192 WP_120171528.1 DNA-directed RNA polymerase subunit beta -
  SR187_RS03495 (SR187_3575) endA 716438..717280 (+) 843 WP_120171529.1 DNA/RNA non-specific endonuclease Machinery gene
  SR187_RS03500 (SR187_3580) - 717469..719022 (+) 1554 WP_120171530.1 MFS transporter -
  SR187_RS03505 (SR187_3585) - 719266..720294 (+) 1029 WP_120171531.1 sugar kinase -
  SR187_RS03510 (SR187_3590) uidA 720310..722100 (+) 1791 WP_120171532.1 beta-glucuronidase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30396.99 Da        Isoelectric Point: 9.7546

>NTDB_id=69449 SR187_RS03495 WP_120171529.1 716438..717280(+) (endA) [Streptococcus ruminantium strain GUT-187]
MAEKNVKKQAMSLFSLLATLIVVGGGYFLSSTTNSNVTNHPYYVNQSKASESVPSQELASSVLTENVKKQLGTKIEWNGA
GAFFINGNKTNLDASVASAPYGENKTKIVQGKMVPTVANALLAKSTRQYKDRDETGKGRTSWTPAGWHQIHGLSGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQASTGQNYFESQIRRALDKNKRVRYRVTLIYAEDNDLIPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYRTGKITVNPH

Nucleotide


Download         Length: 843 bp        

>NTDB_id=69449 SR187_RS03495 WP_120171529.1 716438..717280(+) (endA) [Streptococcus ruminantium strain GUT-187]
GTGGCAGAGAAAAATGTAAAAAAACAAGCCATGAGTTTGTTTAGTTTGTTGGCCACACTCATTGTAGTGGGTGGAGGCTA
CTTTCTAAGCAGTACGACGAATAGTAATGTTACGAATCATCCTTACTACGTCAATCAATCCAAGGCTAGCGAATCAGTAC
CAAGTCAAGAATTGGCTAGCTCAGTATTGACAGAAAATGTAAAAAAGCAACTCGGAACTAAGATTGAGTGGAACGGAGCA
GGTGCTTTCTTCATCAATGGGAATAAAACCAATCTAGATGCATCGGTAGCTAGTGCTCCTTATGGAGAAAATAAAACCAA
GATTGTACAGGGAAAAATGGTACCGACGGTTGCAAATGCTCTTTTAGCAAAATCAACCCGTCAGTACAAGGACCGAGATG
AAACAGGAAAGGGGCGTACCTCTTGGACTCCTGCTGGCTGGCATCAGATTCATGGCTTATCAGGGGAATATGATCATGCA
GTTGATCGAGGCCATTTACTAGGCTATGCCTTGATTGGTGGGCTTTCTGGTTTTGATGCTTCAACAAGCAATCCTAAGAA
CATAGCTGTTCAGACAGCTTGGTCCAATCAAGCCAATGACCAAGCTTCTACCGGGCAAAATTATTTTGAAAGTCAGATTC
GTCGGGCGTTGGATAAAAATAAGCGTGTCCGCTACCGTGTAACACTGATTTATGCAGAGGACAATGACTTGATTCCAGTT
GGGAGTCATTTAGAAGCAAAAGCAGCAGATGGAAGTCTAGAATTTAATGTTTTTGTTCCAAATGTACAAAGTGGTTTGAG
TATCAATTATCGTACTGGTAAGATTACAGTCAATCCCCACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TPR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.234

91.429

0.596
  endA Streptococcus pneumoniae D39

65.234

91.429

0.596
  endA Streptococcus pneumoniae R6

65.234

91.429

0.596
  endA Streptococcus pneumoniae TIGR4

65.234

91.429

0.596

Multiple sequence alignment