NTDB

Overview

Name	endA	Type	Machinery gene
Locus tag	C822_RS10965	Genome accession	NZ_CP097561
Coordinates	2215076..2215912 (+)	Length	278 a.a.
NCBI ID	WP_004049325.1	Uniprot ID	A0A4V1PRC4
Organism	Ligilactobacillus murinus ASF361
Function	cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2210076..2220912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C822_RS10935	-	2210588..2210767 (+)	180	WP_039936126.1	hypothetical protein	-
C822_RS10940 (C822_002209)	-	2211095..2211361 (+)	267	WP_004049336.1	hypothetical protein	-
C822_RS10945 (C822_002210)	-	2212133..2212519 (-)	387	WP_004049334.1	DUF1801 domain-containing protein	-
C822_RS10950 (C822_002211)	-	2212587..2213012 (+)	426	WP_004049332.1	N-acetyltransferase	-
C822_RS10955 (C822_002212)	-	2213181..2213828 (-)	648	WP_004049330.1	nitroreductase	-
C822_RS10960 (C822_002213)	asnA	2214009..2215016 (+)	1008	WP_004049328.1	aspartate--ammonia ligase	-
C822_RS10965 (C822_002214)	endA	2215076..2215912 (+)	837	WP_004049325.1	DNA/RNA non-specific endonuclease	Machinery gene
C822_RS10970 (C822_002215)	-	2215912..2216223 (+)	312	WP_004049323.1	hypothetical protein	-
C822_RS10975 (C822_002216)	-	2216450..2217325 (+)	876	WP_004049321.1	type II CAAX endopeptidase family protein	-
C822_RS10980 (C822_002217)	-	2217457..2218347 (+)	891	WP_004049319.1	ABC transporter ATP-binding protein	-
C822_RS10985 (C822_002218)	-	2218331..2219050 (+)	720	WP_004049317.1	ABC transporter permease	-
C822_RS10990 (C822_002219)	-	2219052..2220188 (+)	1137	WP_004049316.1	histidine kinase	-
C822_RS10995 (C822_002220)	-	2220166..2220771 (+)	606	WP_004049315.1	response regulator transcription factor	-

Sequence

Protein

Download Length: 278 a.a. Molecular weight: 30334.02 Da Isoelectric Point: 10.5647

                                >NTDB_id=690161 C822_RS10965 WP_004049325.1 2215076..2215912(+) (endA) [Ligilactobacillus murinus ASF361]

MKFKKILTGFVAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN

NSGAFIVNNNKTGLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY

DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA

HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

Download Length: 837 bp

                                >NTDB_id=690161 C822_RS10965 WP_004049325.1 2215076..2215912(+) (endA) [Ligilactobacillus murinus ASF361]

ATGAAGTTCAAAAAAATATTGACCGGATTTGTGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA

AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC

CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTAGGCGGTGAGCAAAATCTCAAATGGAAC

AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGGTTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA

AGTCGATAGCTTAAAACGTCCGACGGTAGCTAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA

CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT

GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT

TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA

AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGCGCT

CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAGGGATTAAAGATCGA

CTATGCTACTGGTCATGCGATAAAGGAGAACAACTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-250)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A4V1PRC4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525

Detailed information NTG0690161