Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   OTU45_RS08535 Genome accession   NZ_CP113114
Coordinates   1676830..1677618 (-) Length   262 a.a.
NCBI ID   WP_000940733.1    Uniprot ID   C1CSK2
Organism   Streptococcus pneumoniae strain NP1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671830..1682618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS08505 (OTU45_08505) - 1672817..1673329 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  OTU45_RS08510 (OTU45_08510) - 1673416..1674174 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  OTU45_RS08515 (OTU45_08515) - 1674382..1674552 (+) 171 WP_000403101.1 hypothetical protein -
  OTU45_RS08520 (OTU45_08520) - 1674674..1675804 (-) 1131 WP_000229961.1 ABC transporter ATP-binding protein -
  OTU45_RS08530 (OTU45_08530) - 1676255..1676830 (-) 576 WP_000158722.1 cysteine hydrolase family protein -
  OTU45_RS08535 (OTU45_08535) codY 1676830..1677618 (-) 789 WP_000940733.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  OTU45_RS08540 (OTU45_08540) - 1677883..1679457 (-) 1575 WP_267742465.1 DEAD/DEAH box helicase -
  OTU45_RS08545 (OTU45_08545) - 1679655..1680881 (-) 1227 WP_061754993.1 OFA family MFS transporter -
  OTU45_RS08550 (OTU45_08550) - 1681074..1682390 (+) 1317 WP_061754992.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.15 Da        Isoelectric Point: 5.7806

>NTDB_id=689693 OTU45_RS08535 WP_000940733.1 1676830..1677618(-) (codY) [Streptococcus pneumoniae strain NP1]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=689693 OTU45_RS08535 WP_000940733.1 1676830..1677618(-) (codY) [Streptococcus pneumoniae strain NP1]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTTCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTACCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGAAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CSK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454