Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   OS086_RS12195 Genome accession   NZ_CP113039
Coordinates   2413742..2414515 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain Gwen     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2408742..2419515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS086_RS12175 trmFO 2409085..2410392 (+) 1308 WP_267811032.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  OS086_RS12180 xerC 2410810..2411706 (+) 897 WP_267811033.1 tyrosine recombinase XerC -
  OS086_RS12185 hslV 2411703..2412248 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  OS086_RS12190 hslU 2412314..2413717 (+) 1404 WP_000379044.1 ATP-dependent protease ATPase subunit HslU -
  OS086_RS12195 codY 2413742..2414515 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  OS086_RS12200 - 2414589..2414663 (+) 75 WP_031761472.1 hypothetical protein -
  OS086_RS12205 rpsB 2414862..2415629 (+) 768 WP_267811034.1 30S ribosomal protein S2 -
  OS086_RS12210 - 2415663..2415776 (+) 114 WP_001789890.1 hypothetical protein -
  OS086_RS12215 tsf 2415811..2416692 (+) 882 WP_000201392.1 translation elongation factor Ts -
  OS086_RS12220 pyrH 2416829..2417551 (+) 723 WP_000057330.1 UMP kinase -
  OS086_RS12225 frr 2417570..2418124 (+) 555 WP_001280006.1 ribosome recycling factor -
  OS086_RS12230 - 2418497..2419267 (+) 771 WP_000473699.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=688111 OS086_RS12195 WP_000055337.1 2413742..2414515(+) (codY) [Staphylococcus aureus strain Gwen]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=688111 OS086_RS12195 WP_000055337.1 2413742..2414515(+) (codY) [Staphylococcus aureus strain Gwen]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428