Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   MWG54_RS18820 Genome accession   NZ_CP095377
Coordinates   3707594..3708373 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus cereus strain SEM-15     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3692148..3747213 3707594..3708373 within 0


Gene organization within MGE regions


Location: 3692148..3747213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWG54_RS18765 (MWG54_18765) rimP 3693050..3693520 (-) 471 WP_000359096.1 ribosome maturation factor RimP -
  MWG54_RS18770 (MWG54_18770) - 3693857..3698158 (-) 4302 WP_098283099.1 PolC-type DNA polymerase III -
  MWG54_RS18775 (MWG54_18775) - 3698283..3699983 (-) 1701 WP_000814333.1 proline--tRNA ligase -
  MWG54_RS18780 (MWG54_18780) rseP 3700093..3701349 (-) 1257 WP_001090245.1 RIP metalloprotease RseP -
  MWG54_RS18785 (MWG54_18785) dxr 3701367..3702509 (-) 1143 WP_000790372.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  MWG54_RS18790 (MWG54_18790) cdsA 3702533..3703324 (-) 792 WP_000813592.1 phosphatidate cytidylyltransferase -
  MWG54_RS18795 (MWG54_18795) uppS 3703342..3704118 (-) 777 WP_000971296.1 isoprenyl transferase -
  MWG54_RS18800 (MWG54_18800) frr 3704204..3704761 (-) 558 WP_000531501.1 ribosome recycling factor -
  MWG54_RS18805 (MWG54_18805) pyrH 3704764..3705486 (-) 723 WP_000042668.1 UMP kinase -
  MWG54_RS18810 (MWG54_18810) tsf 3705553..3706440 (-) 888 WP_001018578.1 translation elongation factor Ts -
  MWG54_RS18815 (MWG54_18815) rpsB 3706544..3707245 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  MWG54_RS18820 (MWG54_18820) codY 3707594..3708373 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  MWG54_RS18825 (MWG54_18825) hslU 3708451..3709842 (-) 1392 WP_000550087.1 ATP-dependent protease ATPase subunit HslU -
  MWG54_RS18830 (MWG54_18830) hslV 3709865..3710407 (-) 543 WP_048567505.1 ATP-dependent protease proteolytic subunit HslV -
  MWG54_RS18835 (MWG54_18835) xerC 3710450..3711349 (-) 900 WP_001101241.1 tyrosine recombinase XerC -
  MWG54_RS18840 (MWG54_18840) trmFO 3711415..3712719 (-) 1305 WP_000213002.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  MWG54_RS18845 (MWG54_18845) topA 3712768..3714846 (-) 2079 WP_001286963.1 type I DNA topoisomerase -
  MWG54_RS18850 (MWG54_18850) dprA 3714991..3715860 (-) 870 WP_000818039.1 DNA-processing protein DprA -
  MWG54_RS18855 (MWG54_18855) sucD 3715948..3716850 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  MWG54_RS18860 (MWG54_18860) sucC 3716870..3718030 (-) 1161 WP_001020791.1 ADP-forming succinate--CoA ligase subunit beta -
  MWG54_RS18865 (MWG54_18865) - 3718225..3718998 (-) 774 WP_001194266.1 ribonuclease HII -
  MWG54_RS18870 (MWG54_18870) ylqF 3719055..3719945 (-) 891 WP_000236702.1 ribosome biogenesis GTPase YlqF -
  MWG54_RS18875 (MWG54_18875) lepB 3719966..3720517 (-) 552 WP_000711853.1 signal peptidase I -
  MWG54_RS18880 (MWG54_18880) rplS 3720619..3720963 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  MWG54_RS18885 (MWG54_18885) trmD 3721110..3721844 (-) 735 WP_000686903.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  MWG54_RS18890 (MWG54_18890) rimM 3721844..3722359 (-) 516 WP_000170278.1 ribosome maturation factor RimM -
  MWG54_RS18895 (MWG54_18895) - 3722480..3722707 (-) 228 WP_000737401.1 KH domain-containing protein -
  MWG54_RS18900 (MWG54_18900) rpsP 3722722..3722994 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  MWG54_RS18905 (MWG54_18905) ffh 3723096..3724445 (-) 1350 WP_000863460.1 signal recognition particle protein -
  MWG54_RS18910 (MWG54_18910) - 3724458..3724790 (-) 333 WP_000891062.1 putative DNA-binding protein -
  MWG54_RS18915 (MWG54_18915) ftsY 3724924..3725913 (-) 990 WP_246961013.1 signal recognition particle-docking protein FtsY -
  MWG54_RS18920 (MWG54_18920) smc 3725929..3729498 (-) 3570 WP_047386702.1 chromosome segregation protein SMC -
  MWG54_RS18925 (MWG54_18925) rncS 3729645..3730382 (-) 738 WP_001146875.1 ribonuclease III -
  MWG54_RS18930 (MWG54_18930) acpP 3730441..3730674 (-) 234 WP_000786062.1 acyl carrier protein -
  MWG54_RS18935 (MWG54_18935) fabG 3730744..3731484 (-) 741 WP_000911768.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  MWG54_RS18940 (MWG54_18940) fabD 3731484..3732428 (-) 945 WP_000515903.1 ACP S-malonyltransferase -
  MWG54_RS18945 (MWG54_18945) plsX 3732443..3733435 (-) 993 WP_000684098.1 phosphate acyltransferase PlsX -
  MWG54_RS18950 (MWG54_18950) fapR 3733432..3734025 (-) 594 WP_000747349.1 transcription factor FapR -
  MWG54_RS18955 (MWG54_18955) recG 3734114..3736162 (-) 2049 WP_001000813.1 ATP-dependent DNA helicase RecG -
  MWG54_RS18960 (MWG54_18960) - 3736453..3738129 (-) 1677 WP_000027129.1 DAK2 domain-containing protein -
  MWG54_RS18965 (MWG54_18965) - 3738152..3738514 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  MWG54_RS18970 (MWG54_18970) rpmB 3738891..3739079 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  MWG54_RS18975 (MWG54_18975) spoVM 3739153..3739233 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  MWG54_RS18980 (MWG54_18980) - 3739300..3739980 (-) 681 WP_246961018.1 thiamine diphosphokinase -
  MWG54_RS18985 (MWG54_18985) rpe 3740050..3740694 (-) 645 WP_000589974.1 ribulose-phosphate 3-epimerase -
  MWG54_RS18990 (MWG54_18990) rsgA 3740697..3741578 (-) 882 WP_001113932.1 ribosome small subunit-dependent GTPase A -
  MWG54_RS18995 (MWG54_18995) pknB 3741825..3743798 (-) 1974 WP_000904748.1 Stk1 family PASTA domain-containing Ser/Thr kinase -
  MWG54_RS19000 (MWG54_19000) - 3743807..3744559 (-) 753 WP_000648703.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  MWG54_RS19005 (MWG54_19005) rlmN 3744564..3745652 (-) 1089 WP_000450541.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  MWG54_RS19010 (MWG54_19010) rsmB 3745657..3746991 (-) 1335 WP_246961021.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=676589 MWG54_RS18820 WP_000421290.1 3707594..3708373(-) (codY) [Bacillus cereus strain SEM-15]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=676589 MWG54_RS18820 WP_000421290.1 3707594..3708373(-) (codY) [Bacillus cereus strain SEM-15]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGGAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCAAACGTATTCGTAGTTAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAAAACGAACGCATGAAGCAAATGCTTGCAGAACGTCAATTCCCAGAAGAATATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTGAACAGTGCTTACACAGCATTCCCAGTAGAAAACAGAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCGAT
TGAGCACATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459