Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   OG832_RS28685 Genome accession   NZ_CP108873
Coordinates   6284290..6284952 (+) Length   220 a.a.
NCBI ID   WP_259934725.1    Uniprot ID   A0ABW2WUG4
Organism   Streptomyces sp. NBC_00826     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 6279290..6289952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG832_RS28675 (OG832_28600) - 6281237..6283537 (+) 2301 WP_330434866.1 protein kinase domain-containing protein -
  OG832_RS28680 (OG832_28605) - 6283559..6284170 (-) 612 WP_330434865.1 PepSY domain-containing protein -
  OG832_RS28685 (OG832_28610) ciaR 6284290..6284952 (+) 663 WP_259934725.1 response regulator transcription factor Regulator
  OG832_RS28690 (OG832_28615) - 6284949..6286421 (+) 1473 WP_330434863.1 HAMP domain-containing sensor histidine kinase -
  OG832_RS28695 (OG832_28620) - 6286439..6286915 (-) 477 WP_259934723.1 MarR family winged helix-turn-helix transcriptional regulator -
  OG832_RS28700 (OG832_28625) - 6287039..6287803 (-) 765 WP_266688566.1 AIM24 family protein -
  OG832_RS28705 (OG832_28630) - 6287800..6288450 (-) 651 WP_266688564.1 AIM24 family protein -
  OG832_RS28710 (OG832_28635) - 6288450..6289082 (-) 633 WP_124717356.1 AIM24 family protein -
  OG832_RS28715 (OG832_28640) - 6289330..6289680 (+) 351 WP_093544066.1 DUF3817 domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23790.33 Da        Isoelectric Point: 5.6761

>NTDB_id=667983 OG832_RS28685 WP_259934725.1 6284290..6284952(+) (ciaR) [Streptomyces sp. NBC_00826]
MRLLIVEDEKRLARSLAAGLTAEGFAVDVVHDGLEGLHRAAEGTYDLVVLDIMLPGMNGYRVCAALRAAGHETPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARIRALLRRRGGGSASPVVTVGALRMDTAARRVHLGEAEITLTTKEFAVLE
QLALRSGQVVSKADILEHVWDFAYDGDPNIVEVYVSALRRKLGAAAIRTVRGAGYRLEAL

Nucleotide


Download         Length: 663 bp        

>NTDB_id=667983 OG832_RS28685 WP_259934725.1 6284290..6284952(+) (ciaR) [Streptomyces sp. NBC_00826]
ATGCGCCTGTTGATCGTGGAGGACGAGAAGCGGCTCGCGAGGTCCCTGGCCGCGGGGCTCACCGCCGAGGGCTTCGCCGT
GGACGTCGTGCACGACGGCCTCGAAGGGCTGCACCGTGCCGCCGAGGGGACGTACGACCTCGTCGTCCTCGACATCATGC
TGCCCGGGATGAACGGCTACCGGGTCTGTGCCGCGCTGCGCGCCGCCGGGCACGAGACGCCGATCCTGATGCTCACGGCG
AAGGACGGCGAGTACGACGAGGCGGAGGGCCTGGACACCGGGGCCGACGACTATCTGACCAAGCCCTTCTCGTACGTCGT
GCTGGTGGCCAGGATCCGGGCGCTGCTGCGGCGCCGGGGCGGCGGCTCCGCCTCACCGGTGGTCACCGTCGGCGCCCTGC
GCATGGACACCGCCGCCCGCCGCGTCCACCTCGGCGAGGCCGAGATCACCCTGACCACCAAGGAGTTCGCGGTGCTGGAA
CAGCTCGCACTGCGGTCCGGGCAGGTGGTGAGCAAGGCGGACATCCTCGAACACGTCTGGGACTTCGCCTACGACGGCGA
CCCGAACATCGTCGAGGTGTACGTGAGCGCGCTGCGCCGCAAGCTCGGCGCGGCCGCCATCCGCACGGTGCGCGGCGCCG
GGTACCGGCTGGAGGCGCTGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-217)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

40.807

100

0.414
  covR Streptococcus salivarius strain HSISS4

40.541

100

0.409
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.271

100

0.405
  vicR Streptococcus mutans UA159

37.931

100

0.4
  micA Streptococcus pneumoniae Cp1015

37.021

100

0.395
  ciaR Streptococcus pneumoniae D39

38.565

100

0.391
  ciaR Streptococcus pneumoniae R6

38.565

100

0.391
  ciaR Streptococcus pneumoniae TIGR4

38.565

100

0.391
  ciaR Streptococcus pneumoniae Rx1

38.565

100

0.391

Multiple sequence alignment