Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   MPG61_RS00865 Genome accession   NZ_CP094148
Coordinates   184460..185203 (+) Length   247 a.a.
NCBI ID   WP_000660524.1    Uniprot ID   A0AAI8F143
Organism   Helicobacter pylori strain Hpfe024     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 179460..190203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MPG61_RS00840 (MPG61_00840) panD 181629..181982 (+) 354 WP_220925212.1 aspartate 1-decarboxylase -
  MPG61_RS00845 (MPG61_00845) - 181985..182278 (+) 294 WP_048944407.1 YbaB/EbfC family nucleoid-associated protein -
  MPG61_RS00850 (MPG61_00850) - 182278..183273 (+) 996 WP_245020787.1 PDZ domain-containing protein -
  MPG61_RS00855 (MPG61_00855) comB6 183279..184334 (+) 1056 WP_245020515.1 P-type conjugative transfer protein TrbL Machinery gene
  MPG61_RS00860 (MPG61_00860) comB7 184350..184463 (+) 114 WP_245020516.1 comB7 lipoprotein Machinery gene
  MPG61_RS00865 (MPG61_00865) comB8 184460..185203 (+) 744 WP_000660524.1 virB8 family protein Machinery gene
  MPG61_RS00870 (MPG61_00870) comB9 185203..186165 (+) 963 WP_220925210.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  MPG61_RS00875 (MPG61_00875) comB10 186158..187294 (+) 1137 WP_245020517.1 DNA type IV secretion system protein ComB10 Machinery gene
  MPG61_RS00880 (MPG61_00880) - 187364..188776 (+) 1413 WP_245020518.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  MPG61_RS00885 (MPG61_00885) gmd 188790..189935 (+) 1146 WP_050853660.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=667614 MPG61_RS00865 WP_000660524.1 184460..185203(+) (comB8) [Helicobacter pylori strain Hpfe024]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=667614 MPG61_RS00865 WP_000660524.1 184460..185203(+) (comB8) [Helicobacter pylori strain Hpfe024]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAAGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCACAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTCATGAATGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCACCAACTAATAGAGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment