Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SCSC_RS03200 Genome accession   NZ_AP014647
Coordinates   648261..649106 (+) Length   281 a.a.
NCBI ID   WP_003072166.1    Uniprot ID   A0AAD2SW28
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 643261..654106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS03170 (SCSC_0657) - 643628..644506 (+) 879 WP_003069751.1 F0F1 ATP synthase subunit gamma -
  SCSC_RS03175 (SCSC_0658) atpD 644541..645947 (+) 1407 WP_003030503.1 F0F1 ATP synthase subunit beta -
  SCSC_RS03180 (SCSC_0659) - 645958..646377 (+) 420 WP_003069748.1 F0F1 ATP synthase subunit epsilon -
  SCSC_RS03185 - 646481..646711 (+) 231 WP_080572555.1 DUF1146 family protein -
  SCSC_RS03190 (SCSC_0661) murA 646749..648029 (+) 1281 WP_006269932.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SCSC_RS03195 (SCSC_0662) - 648022..648198 (+) 177 WP_003072163.1 DNA-directed RNA polymerase subunit beta -
  SCSC_RS03200 (SCSC_0663) endA 648261..649106 (+) 846 WP_003072166.1 DNA/RNA non-specific endonuclease Machinery gene
  SCSC_RS03205 (SCSC_0664) - 649260..650996 (+) 1737 WP_006269922.1 ABC transporter ATP-binding protein -
  SCSC_RS03210 (SCSC_0665) - 651006..652775 (+) 1770 WP_006269913.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30714.35 Da        Isoelectric Point: 10.3160

>NTDB_id=66560 SCSC_RS03200 WP_003072166.1 648261..649106(+) (endA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MSQRKSNQKVMQSVIGGIIALSLALGAYYFRANNNGTVHQDSSAINKSLEQHHAGPSKDLAQSVLTGNVRSQFKGKIEWN
GAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGEYH
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANASHSTGQNFYETKVRKALDKNKRVRYRVTLIYASEQDLV
PVGSHIEAKSSDGSLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=66560 SCSC_RS03200 WP_003072166.1 648261..649106(+) (endA) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGTCGCAGAGAAAATCCAATCAAAAAGTAATGCAGAGTGTTATTGGAGGGATTATTGCACTTAGTTTAGCTCTTGGTGC
TTATTATTTTCGAGCAAATAATAATGGTACAGTTCATCAAGATAGTTCTGCCATTAACAAAAGTCTCGAGCAACATCATG
CGGGTCCTAGTAAAGATCTGGCTCAAAGTGTATTGACAGGTAATGTGCGTTCACAATTTAAAGGGAAAATCGAGTGGAAT
GGCGCAGGGGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGAAGTATTCCTTATGCGGATAATAA
GACAAAATTGGTCAGAGGTCGAACTGTTCCAACGGTAGCAAATGCTCTTTTGTCCAAAGCTACTCGTCAGTATAGGAATC
GTGAAGAAACAGGTAATGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCGGGTGAATATCAT
CATGCAGTTGACCGTGGACATCTGCTAGGTTATGCCTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACTAGCAATCC
TAAAAATATTGCGGTGCAAACGGCTTGGGCGAATCAAGCAAATGCTAGCCATTCTACAGGTCAAAATTTTTATGAAACGA
AAGTACGTAAAGCTCTTGATAAAAATAAACGAGTTCGGTATCGAGTGACCTTGATTTACGCAAGTGAGCAGGATTTAGTA
CCGGTTGGTTCACATATTGAAGCCAAGTCTAGCGACGGTAGTTTGGAAATAAATGTCTTTGTGCCAAACGTACAGACAGG
AATTCGATTAAATTATCAGACAGGAGAAGTGACGGTCACCAACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(112-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.613

97.509

0.669
  endA Streptococcus pneumoniae D39

68.613

97.509

0.669
  endA Streptococcus pneumoniae R6

68.613

97.509

0.669
  endA Streptococcus pneumoniae TIGR4

68.613

97.509

0.669

Multiple sequence alignment