Detailed information NTG0660053

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MKF36_RS16545
• Genome accession: NZ_CP092750
• Coordinates: 3358358..3359521 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain KS04AU
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3353358..3364521

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKF36_RS16515 (MKF36_16515)	-	3353622..3354041 (-)	420	WP_042635530.1	TIGR03826 family flagellar region protein	-
MKF36_RS16520 (MKF36_16520)	comFC	3354115..3354804 (-)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
MKF36_RS16525 (MKF36_16525)	-	3354810..3355094 (-)	285	WP_007407481.1	competence protein ComFB	-
MKF36_RS16530 (MKF36_16530)	comFA	3355152..3356537 (-)	1386	WP_042635531.1	DEAD/DEAH box helicase	Machinery gene
MKF36_RS16535 (MKF36_16535)	-	3356646..3357494 (-)	849	WP_007407483.1	DegV family protein	-
MKF36_RS16540 (MKF36_16540)	degU	3357592..3358281 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MKF36_RS16545 (MKF36_16545)	degS	3358358..3359521 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MKF36_RS16550 (MKF36_16550)	-	3359744..3360391 (+)	648	WP_007614107.1	YigZ family protein	-
MKF36_RS16555 (MKF36_16555)	-	3360396..3361616 (+)	1221	WP_020956419.1	LCP family protein	-
MKF36_RS16560 (MKF36_16560)	-	3361723..3362799 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
MKF36_RS16565 (MKF36_16565)	-	3362932..3364128 (-)	1197	WP_042635532.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=660053 MKF36_RS16545 WP_007407484.1 3358358..3359521(-) (degS) [Bacillus velezensis strain KS04AU]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=660053 MKF36_RS16545 WP_007407484.1 3358358..3359521(-) (degS) [Bacillus velezensis strain KS04AU]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCTTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTGATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951