Detailed information NTG0065241

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: BEST7003_RS08445
• Genome accession: NZ_AP012496
• Coordinates: 1671720..1672499 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis BEST7003
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1666720..1677499

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BEST7003_RS08425 (BEST7003_1634)	trmFO	1667413..1668720 (+)	1308	WP_003244725.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
BEST7003_RS08430 (BEST7003_1635)	xerC	1668788..1669702 (+)	915	WP_003231988.1	tyrosine recombinase XerC	-
BEST7003_RS08435 (BEST7003_1636)	clpQ	1669715..1670260 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
BEST7003_RS08440 (BEST7003_1637)	hslU	1670277..1671680 (+)	1404	WP_003245556.1	HslU--HslV peptidase ATPase subunit	-
BEST7003_RS08445 (BEST7003_1638)	codY	1671720..1672499 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
BEST7003_RS08450 (BEST7003_1639)	flgB	1672879..1673268 (+)	390	WP_003245656.1	flagellar basal body rod protein FlgB	-
BEST7003_RS08455 (BEST7003_1640)	flgC	1673268..1673720 (+)	453	WP_003245521.1	flagellar basal body rod protein FlgC	-
BEST7003_RS08460 (BEST7003_1641)	fliE	1673731..1674051 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
BEST7003_RS08465 (BEST7003_1642)	fliF	1674097..1675707 (+)	1611	WP_010886506.1	flagellar basal-body MS-ring/collar protein FliF	-
BEST7003_RS08470 (BEST7003_1643)	fliG	1675720..1676736 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
BEST7003_RS08475 (BEST7003_1644)	fliH	1676729..1677481 (+)	753	WP_003244804.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=65241 BEST7003_RS08445 WP_003220850.1 1671720..1672499(+) (codY) [Bacillus subtilis BEST7003]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=65241 BEST7003_RS08445 WP_003220850.1 1671720..1672499(+) (codY) [Bacillus subtilis BEST7003]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCAATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCCTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467