Detailed information NTG0645614

Bioinformatically predicted

Overview

• Name: amiF
• Type: Regulator
• Locus tag: L1A12_RS08590
• Genome accession: NZ_CP090882
• Coordinates: 1696433..1697359 (-)
• Length: 308 a.a.
• NCBI ID: WP_001291296.1
• Uniprot ID: A0A0T8U5M2
• Organism: Streptococcus pneumoniae strain CH2241
• Function: internalize XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1695032..1696358	1696433..1697359	flank	75

Gene organization within MGE regions

Location: 1695032..1697359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A12_RS08585 (L1A12_08585)	-	1695032..1696358 (+)	1327	Protein_1714	transposase	-
L1A12_RS08590 (L1A12_08590)	amiF	1696433..1697359 (-)	927	WP_001291296.1	ATP-binding cassette domain-containing protein	Regulator

Sequence

Protein

• Length: 308 a.a.
• Molecular weight: 34769.82 Da
• Isoelectric Point: 6.6224

>NTDB_id=645614 L1A12_RS08590 WP_001291296.1 1696433..1697359(-) (amiF) [Streptococcus pneumoniae strain CH2241]
MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGESGSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSRE
QAAELIRRIQMIFQDPAASLNERATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFISDRIAVIYKGVIVEVAETEELFN
NPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHDYETDKPSMVEIRPGHYVWANQAELARYQKGLN

Nucleotide

• Length: 927 bp

>NTDB_id=645614 L1A12_RS08590 WP_001291296.1 1696433..1697359(-) (amiF) [Streptococcus pneumoniae strain CH2241]
ATGTCTGAAAAATTAGTAGAAATCAAAGATTTAGAAATTTCCTTCGGTGAAGGAAGTAAGAAGTTTGTCGCGGTTAAAAA
TGCTAACTTCTTTATCAACAAGGGAGAAACTTTCTCGCTTGTAGGTGAGTCCGGTAGTGGGAAAACAACTATTGGTCGTG
CTATCATCGGTCTAAATGATACAAGTAATGGAGATATCATTTTTGATGGTCAAAAGATTAATGGTAAGAAATCGCGTGAA
CAAGCTGCGGAATTGATTCGTCGAATCCAGATGATTTTCCAAGACCCTGCCGCAAGTTTGAATGAACGTGCGACTGTTGA
TTATATTATTTCTGAAGGTCTTTACAATCACCGTTTATTTAAGGATGAAGAAGAACGTAAAGAGAAAGTTCAAAGTATTA
TCCGTGAAGTAGGTCTTCTTGCTGAGCACTTGACTCGTTACCCTCATGAATTCTCAGGCGGTCAACGTCAACGTATCGGT
ATTGCCCGTGCCTTGGTCATGCAACCAGACTTTGTTATTGCAGATGAGCCAATTTCAGCCTTGGACGTTTCTGTACGTGC
CCAAGTCTTGAACTTGCTCAAAAAATTCCAAAAAGAGCTCGGCTTGACCTATCTCTTCATCGCCCATGACTTGTCGGTTG
TTCGCTTTATTTCAGATCGTATCGCAGTTATTTACAAGGGTGTTATTGTAGAGGTTGCAGAAACAGAAGAATTGTTTAAC
AATCCAATTCACCCATATACTCAAGCCTTGCTTTCAGCAGTACCAATCCCAGATCCAATCTTGGAACGTAAGAAGGTCTT
GAAGGTTTACGACCCAAGTCAACACGACTATGAGACTGATAAGCCATCTATGGTAGAAATCCGTCCAGGTCACTATGTTT
GGGCGAACCAAGCCGAATTGGCACGTTATCAAAAAGGACTAAACTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (25-178)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (230-262)

3D structure

• AlphaFold DB: A0A0T8U5M2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiF	Streptococcus thermophilus LMG 18311	85.574	99.026	0.847
amiF	Streptococcus salivarius strain HSISS4	85.574	99.026	0.847
amiF	Streptococcus thermophilus LMD-9	85.246	99.026	0.844