Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   LL229_RS01500 Genome accession   NZ_CP090823
Coordinates   242288..243076 (+) Length   262 a.a.
NCBI ID   WP_003129722.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain 229     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 239162..258806 242288..243076 within 0


Gene organization within MGE regions


Location: 239162..258806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL229_RS01490 (LL229_0254) - 239269..240852 (+) 1584 WP_010905162.1 APC family permease -
  LL229_RS01495 (LL229_0255) - 240921..242135 (+) 1215 WP_003129721.1 pyridoxal phosphate-dependent aminotransferase -
  LL229_RS01500 (LL229_0256) codY 242288..243076 (+) 789 WP_003129722.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  LL229_RS01505 (LL229_0257) gatC 243585..243890 (+) 306 WP_010905163.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  LL229_RS01510 (LL229_0258) gatA 243890..245350 (+) 1461 WP_010905164.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  LL229_RS01515 (LL229_0259) - 245354..245956 (+) 603 WP_010905165.1 NUDIX hydrolase N-terminal domain-containing protein -
  LL229_RS01520 (LL229_0260) gatB 245996..247429 (+) 1434 WP_010905166.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  LL229_RS01525 (LL229_0262) - 247653..249152 (+) 1500 WP_010905167.1 amidase family protein -
  LL229_RS01530 (LL229_0263) - 249234..250574 (-) 1341 WP_010905168.1 MATE family efflux transporter -
  LL229_RS01535 (LL229_0264) - 250756..250953 (-) 198 WP_003129735.1 cold-shock protein -
  LL229_RS01540 (LL229_0265) - 251071..251604 (+) 534 WP_010905169.1 5-formyltetrahydrofolate cyclo-ligase -
  LL229_RS01545 (LL229_0266) - 251594..252286 (+) 693 WP_003129738.1 rhomboid family intramembrane serine protease -
  LL229_RS01550 (LL229_0267) - 252386..252817 (+) 432 WP_010905170.1 DUF3284 domain-containing protein -
  LL229_RS01555 (LL229_0268) eis 253208..254260 (+) 1053 WP_010905171.1 enhanced intracellular survival protein Eis -
  LL229_RS01560 (LL229_0269) - 254593..255687 (+) 1095 WP_010905172.1 DUF871 domain-containing protein -
  LL229_RS01565 (LL229_0270) - 255785..257269 (+) 1485 WP_012897016.1 PTS sugar transporter subunit IIC -
  LL229_RS01570 (LL229_0271) - 257394..257600 (+) 207 WP_010905174.1 hypothetical protein -
  LL229_RS01575 (LL229_0272) - 257597..257791 (+) 195 WP_012897017.1 hypothetical protein -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29128.46 Da        Isoelectric Point: 4.5254

>NTDB_id=644941 LL229_RS01500 WP_003129722.1 242288..243076(+) (codY) [Lactococcus lactis subsp. lactis strain 229]
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYV
RAAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSN
LKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
MKGTYLKVLNTGLFDKLAGRNF

Nucleotide


Download         Length: 789 bp        

>NTDB_id=644941 LL229_RS01500 WP_003129722.1 242288..243076(+) (codY) [Lactococcus lactis subsp. lactis strain 229]
GTGGCTACATTACTTGAAAAAACACGTAAAATCACCGCGATTTTGCAAGATGGAGTGACCGATTTGCAACAAGAGTTGCC
ATATAACAGTATGACTGAACGCTTGGCAAACGTCATTGATTGCAATGCATGTGTGATTAATACGAAGGGCGAGTTGCTTG
GTTACTCATTGCCTTATAATACAAACAATGACCGTGTTGACCAATTTTTCTATGATCGTAAATTGCCTGATGAATATGTT
CGTGCGGCAGTACGTATCTACGATACAATGGCAAACGTTCCTGTTGACCGTCCATTAGCAATCTTCCCAGAAGAAAGCCT
TGGCGATTTTCCAAAAGGTGTGACAACTTTAGCACCTATTTATGGTTCTGGAATGCGTTTGGGAACATTTATCATGTGGC
GTGAAGACGGCGAATTCACTGATGATGATTTGGTCTTAGTTGAACTTGCAACAACAGTAATTGGTGTTCAACTCTCAAAT
CTTAAACTTGAACAAATGGAAGAAAATATCCGTAAAGACACCATGGCAACTATGGCTGTTAACACACTTTCATATTCAGA
AATGAAAGCTGTTAAAGCAATCATTGAAGAGCTTGATGGTGAAGAAGGGCATGTTATCGCTTCTGTCATTGCTGACAAGA
TTGGGATTACACGTTCAGTCATCGTTAACGCTTTGCGTAAACTCGAATCTGCTGGTGTAATTGAATCACGTTCACTTGGT
ATGAAAGGAACTTATCTTAAAGTTCTTAATACTGGTTTATTTGATAAACTTGCAGGACGTAATTTCTAA

Domains

Predicted by InterproScan.

CodY helix-turn-helix domain (HTH_CodY)

(201-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

100

100

1
  codY Bacillus subtilis subsp. subtilis str. 168

47.638

96.947

0.462