Detailed information NTG0643517

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: OFY20_RS04095
• Genome accession: NZ_CP107524
• Coordinates: 729712..730497 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain SA5087
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 724712..735497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OFY20_RS04065 (OFY20_04065)	-	725829..726272 (+)	444	WP_001048166.1	hypothetical protein	-
OFY20_RS04070 (OFY20_04070)	-	726357..726623 (+)	267	WP_001865676.1	hypothetical protein	-
OFY20_RS04075 (OFY20_04075)	-	726724..726852 (+)	129	WP_000962057.1	hypothetical protein	-
OFY20_RS04080 (OFY20_04080)	-	726861..727181 (+)	321	WP_001865677.1	hypothetical protein	-
OFY20_RS04085 (OFY20_04085)	-	727278..727949 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
OFY20_RS04090 (OFY20_04090)	-	728006..729451 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
OFY20_RS04095 (OFY20_04095)	endA	729712..730497 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
OFY20_RS04100 (OFY20_04100)	-	730575..731213 (-)	639	WP_000478529.1	VTT domain-containing protein	-
OFY20_RS04105 (OFY20_04105)	-	731430..732086 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
OFY20_RS04110 (OFY20_04110)	-	732083..732856 (+)	774	WP_000012390.1	ABC transporter permease	-
OFY20_RS04115 (OFY20_04115)	-	733020..733838 (+)	819	WP_000601007.1	hypothetical protein	-
OFY20_RS04120 (OFY20_04120)	-	733875..734759 (-)	885	WP_000354840.1	LysR family transcriptional regulator	-
OFY20_RS04125 (OFY20_04125)	-	734952..735458 (+)	507	Protein_733	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=643517 OFY20_RS04095 WP_000825431.1 729712..730497(+) (endA) [Streptococcus agalactiae strain SA5087]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=643517 OFY20_RS04095 WP_000825431.1 729712..730497(+) (endA) [Streptococcus agalactiae strain SA5087]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391