Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   LUA78_RS01790 Genome accession   NZ_CP089283
Coordinates   392684..392968 (+) Length   94 a.a.
NCBI ID   WP_000736106.1    Uniprot ID   T0F3N0
Organism   Helicobacter pylori strain J99 derivative isolate D1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 387684..397968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUA78_RS01765 (LUA78_01765) - 389567..390583 (+) 1017 WP_001061518.1 ArdC-like ssDNA-binding domain-containing protein -
  LUA78_RS01770 (LUA78_01770) - 390590..391141 (+) 552 Protein_347 hypothetical protein -
  LUA78_RS01775 (LUA78_01775) - 391195..391983 (+) 789 WP_234618101.1 integrase -
  LUA78_RS01780 (LUA78_01780) - 391986..392216 (+) 231 WP_000189076.1 hypothetical protein -
  LUA78_RS01785 (LUA78_01785) - 392209..392706 (+) 498 WP_234618102.1 hypothetical protein -
  LUA78_RS01790 (LUA78_01790) comB2 392684..392968 (+) 285 WP_000736106.1 TrbC/VirB2 family protein Machinery gene
  LUA78_RS01795 (LUA78_01795) comB3 392980..393243 (+) 264 WP_234618103.1 competence protein ComB Machinery gene
  LUA78_RS01800 (LUA78_01800) - 393255..393488 (+) 234 WP_234618104.1 hypothetical protein -
  LUA78_RS01805 (LUA78_01805) - 393488..396064 (+) 2577 WP_234618105.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  LUA78_RS01810 (LUA78_01810) - 396061..396201 (+) 141 WP_000789929.1 hypothetical protein -
  LUA78_RS01815 (LUA78_01815) - 396194..397330 (+) 1137 WP_234618106.1 VirB8/TrbF family protein -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10752.11 Da        Isoelectric Point: 11.1589

>NTDB_id=636091 LUA78_RS01790 WP_000736106.1 392684..392968(+) (comB2) [Helicobacter pylori strain J99 derivative isolate D1]
MKKLRHFRKLIAFLGFSPLLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF

Nucleotide


Download         Length: 285 bp        

>NTDB_id=636091 LUA78_RS01790 WP_000736106.1 392684..392968(+) (comB2) [Helicobacter pylori strain J99 derivative isolate D1]
ATGAAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCTCTTTTATTACAAGCGGATATGACTAC
CTTTTTTAATTCCATTGAACAACAGCTCACTAGCCCTACGGCTAAAGGCATTTTAATGGTTATTTTTTTAGGACTTGCTA
TTTTTATATGGAAAAACTTAGATAGATGGAAAGAAATTTTAATGACCGTGCTTGCTATTGCAATTGGTGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAACTGGTTTATGAGTATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(4-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T0F3N0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

57.778

95.745

0.553