Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   FNL60_RS01900 Genome accession   NZ_AP019720
Coordinates   360441..361226 (+) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans strain NBRC 13955     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 355441..366226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS01880 (SM3g_03340) - 356195..357580 (+) 1386 WP_002268948.1 Cof-type HAD-IIB family hydrolase -
  FNL60_RS01885 (SM3g_03350) - 357858..358307 (-) 450 WP_002263469.1 universal stress protein -
  FNL60_RS01890 (SM3g_03360) - 358405..358941 (-) 537 WP_002279914.1 biotin transporter BioY -
  FNL60_RS01895 (SM3g_03370) - 359118..360332 (+) 1215 WP_002263471.1 pyridoxal phosphate-dependent aminotransferase -
  FNL60_RS01900 (SM3g_03380) codY 360441..361226 (+) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  FNL60_RS01905 (SM3g_03390) - 361228..361779 (+) 552 WP_002263473.1 cysteine hydrolase family protein -
  FNL60_RS01910 (SM3g_03400) aspS 362037..363788 (+) 1752 WP_002263474.1 aspartate--tRNA ligase -
  FNL60_RS01915 (SM3g_03410) gatC 363915..364217 (+) 303 WP_002263475.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  FNL60_RS01920 (SM3g_03420) gatA 364217..365683 (+) 1467 WP_002263829.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=62463 FNL60_RS01900 WP_002263472.1 360441..361226(+) (codY) [Streptococcus mutans strain NBRC 13955]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=62463 FNL60_RS01900 WP_002263472.1 360441..361226(+) (codY) [Streptococcus mutans strain NBRC 13955]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCGGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACTATTGCTCCCATCTATGGCGGCGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTCTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAAGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACTTATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471

Multiple sequence alignment