Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   LK685_RS03405 Genome accession   NZ_CP086061
Coordinates   665077..665670 (-) Length   197 a.a.
NCBI ID   WP_003228214.1    Uniprot ID   A0A199WEF2
Organism   Bacillus sp. BC1-43     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 660077..670670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK685_RS03390 (LK685_03395) mdxK 660393..662666 (+) 2274 WP_229762652.1 maltose phosphorylase -
  LK685_RS03395 (LK685_03400) malL 662659..664344 (+) 1686 WP_128993442.1 oligo-1,6-glucosidase -
  LK685_RS03400 (LK685_03405) pgmB 664341..665015 (+) 675 WP_229762653.1 beta-phosphoglucomutase -
  LK685_RS03405 (LK685_03410) clpP 665077..665670 (-) 594 WP_003228214.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  LK685_RS03415 (LK685_03420) cotR 666298..667260 (-) 963 WP_015251166.1 sporulation hydrolase CotR -
  LK685_RS03420 (LK685_03425) - 667616..668959 (+) 1344 WP_029725961.1 FAD-binding oxidoreductase -
  LK685_RS03425 (LK685_03430) - 669211..669723 (+) 513 WP_080529823.1 DUF3231 family protein -
  LK685_RS03430 (LK685_03435) - 669759..670079 (-) 321 WP_003228222.1 QacE family quaternary ammonium compound efflux SMR transporter -
  LK685_RS03435 (LK685_03440) - 670079..670414 (-) 336 WP_014480966.1 SMR family transporter -

Sequence

Protein


Download         Length: 197 a.a.        Molecular weight: 21682.00 Da        Isoelectric Point: 4.9416

>NTDB_id=622151 LK685_RS03405 WP_003228214.1 665077..665670(-) (clpP) [Bacillus sp. BC1-43]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=622151 LK685_RS03405 WP_003228214.1 665077..665670(-) (clpP) [Bacillus sp. BC1-43]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCTAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

100

100

1
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

95.431

0.655
  clpP Streptococcus thermophilus LMG 18311

58.163

99.492

0.579
  clpP Streptococcus thermophilus LMD-9

58.163

99.492

0.579
  clpP Streptococcus pneumoniae D39

57.812

97.462

0.563
  clpP Streptococcus pneumoniae Rx1

57.812

97.462

0.563
  clpP Streptococcus pneumoniae R6

57.812

97.462

0.563
  clpP Streptococcus pneumoniae TIGR4

57.812

97.462

0.563
  clpP Lactococcus lactis subsp. cremoris KW2

57.895

96.447

0.558
  clpP Streptococcus pyogenes JRS4

56.122

99.492

0.558
  clpP Streptococcus pyogenes MGAS315

56.122

99.492

0.558
  clpP Streptococcus mutans UA159

54.822

100

0.548
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.789

96.447

0.538