Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   LIS80_RS18565 Genome accession   NZ_CP085413
Coordinates   3628204..3628983 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus paranthracis strain KF11     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3601585..3647617 3628204..3628983 within 0


Gene organization within MGE regions


Location: 3601585..3647617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIS80_RS18445 (LIS80_18475) - 3601779..3602030 (-) 252 WP_001239754.1 YlmC/YmxH family sporulation protein -
  LIS80_RS18450 (LIS80_18480) - 3602157..3603398 (-) 1242 WP_000592995.1 pitrilysin family protein -
  LIS80_RS18455 (LIS80_18485) - 3603485..3604384 (-) 900 WP_000647527.1 polysaccharide deacetylase family protein -
  LIS80_RS18460 (LIS80_18490) pnp 3604536..3606674 (-) 2139 WP_000076746.1 polyribonucleotide nucleotidyltransferase -
  LIS80_RS18465 (LIS80_18495) rpsO 3606835..3607104 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  LIS80_RS18470 (LIS80_18500) ribF 3607205..3608176 (-) 972 WP_000766710.1 bifunctional riboflavin kinase/FAD synthetase -
  LIS80_RS18475 (LIS80_18505) truB 3608220..3609143 (-) 924 WP_000399358.1 tRNA pseudouridine(55) synthase TruB -
  LIS80_RS18480 (LIS80_18510) rbfA 3609230..3609586 (-) 357 WP_000776443.1 30S ribosome-binding factor RbfA -
  LIS80_RS18485 (LIS80_18515) - 3609602..3609883 (-) 282 WP_000582364.1 DUF503 family protein -
  LIS80_RS18490 (LIS80_18520) infB 3609880..3611940 (-) 2061 WP_000036342.1 translation initiation factor IF-2 -
  LIS80_RS18495 (LIS80_18525) - 3611945..3612256 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  LIS80_RS18500 (LIS80_18530) - 3612257..3612529 (-) 273 WP_000071128.1 YlxR family protein -
  LIS80_RS18505 (LIS80_18535) nusA 3612541..3613647 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  LIS80_RS18510 (LIS80_18540) rimP 3613665..3614135 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  LIS80_RS18515 (LIS80_18545) - 3614468..3618769 (-) 4302 WP_000059980.1 PolC-type DNA polymerase III -
  LIS80_RS18520 (LIS80_18550) - 3618894..3620594 (-) 1701 WP_000814304.1 proline--tRNA ligase -
  LIS80_RS18525 (LIS80_18555) rseP 3620704..3621960 (-) 1257 WP_001090248.1 RIP metalloprotease RseP -
  LIS80_RS18530 (LIS80_18560) dxr 3621977..3623119 (-) 1143 WP_000790352.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  LIS80_RS18535 (LIS80_18565) cdsA 3623143..3623934 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  LIS80_RS18540 (LIS80_18570) uppS 3623952..3624728 (-) 777 WP_000971300.1 isoprenyl transferase -
  LIS80_RS18545 (LIS80_18575) frr 3624814..3625371 (-) 558 WP_000531500.1 ribosome recycling factor -
  LIS80_RS18550 (LIS80_18580) pyrH 3625374..3626096 (-) 723 WP_000042663.1 UMP kinase -
  LIS80_RS18555 (LIS80_18585) tsf 3626163..3627050 (-) 888 WP_001018580.1 translation elongation factor Ts -
  LIS80_RS18560 (LIS80_18590) rpsB 3627154..3627855 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  LIS80_RS18565 (LIS80_18595) codY 3628204..3628983 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  LIS80_RS18570 (LIS80_18600) hslU 3629061..3630452 (-) 1392 WP_000550081.1 ATP-dependent protease ATPase subunit HslU -
  LIS80_RS18575 (LIS80_18605) hslV 3630475..3631017 (-) 543 WP_000526273.1 ATP-dependent protease proteolytic subunit HslV -
  LIS80_RS18580 (LIS80_18610) xerC 3631060..3631959 (-) 900 WP_001101228.1 tyrosine recombinase XerC -
  LIS80_RS18585 (LIS80_18615) trmFO 3632025..3633329 (-) 1305 WP_012644562.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  LIS80_RS18590 (LIS80_18620) topA 3633380..3635458 (-) 2079 WP_088296495.1 type I DNA topoisomerase -
  LIS80_RS18595 (LIS80_18625) dprA 3635603..3636472 (-) 870 WP_000818030.1 DNA-processing protein DprA -
  LIS80_RS18600 (LIS80_18630) sucD 3636560..3637462 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  LIS80_RS18605 (LIS80_18635) sucC 3637482..3638642 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  LIS80_RS18610 (LIS80_18640) rnhB 3638836..3639609 (-) 774 WP_001174724.1 ribonuclease HII -
  LIS80_RS18615 (LIS80_18645) ylqF 3639662..3640552 (-) 891 WP_000236698.1 ribosome biogenesis GTPase YlqF -
  LIS80_RS18620 (LIS80_18650) lepB 3640573..3641124 (-) 552 WP_000711857.1 signal peptidase I -
  LIS80_RS18625 (LIS80_18655) rplS 3641226..3641570 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  LIS80_RS18630 (LIS80_18660) trmD 3641717..3642451 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  LIS80_RS18635 (LIS80_18665) rimM 3642451..3642966 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  LIS80_RS18640 (LIS80_18670) - 3643088..3643315 (-) 228 WP_000737403.1 KH domain-containing protein -
  LIS80_RS18645 (LIS80_18675) rpsP 3643330..3643602 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  LIS80_RS18650 (LIS80_18680) ffh 3643703..3645052 (-) 1350 WP_000863464.1 signal recognition particle protein -
  LIS80_RS18655 (LIS80_18685) - 3645065..3645397 (-) 333 WP_000891062.1 putative DNA-binding protein -
  LIS80_RS18660 (LIS80_18690) ftsY 3645531..3646520 (-) 990 WP_000007646.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=617923 LIS80_RS18565 WP_000421288.1 3628204..3628983(-) (codY) [Bacillus paranthracis strain KF11]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=617923 LIS80_RS18565 WP_000421288.1 3628204..3628983(-) (codY) [Bacillus paranthracis strain KF11]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGCTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATTGAAGAAGAAGCGCGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGTGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459