Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   LIS81_RS18810 Genome accession   NZ_CP085399
Coordinates   3690106..3690885 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus tropicus strain CK18     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3663836..3709748 3690106..3690885 within 0


Gene organization within MGE regions


Location: 3663836..3709748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIS81_RS18695 (LIS81_18710) - 3664057..3665298 (-) 1242 WP_000592994.1 pitrilysin family protein -
  LIS81_RS18700 (LIS81_18715) - 3665385..3666284 (-) 900 WP_000647528.1 polysaccharide deacetylase family protein -
  LIS81_RS18705 (LIS81_18720) pnp 3666436..3668574 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  LIS81_RS18710 (LIS81_18725) rpsO 3668735..3669004 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  LIS81_RS18715 (LIS81_18730) ribF 3669105..3670076 (-) 972 WP_000766719.1 bifunctional riboflavin kinase/FAD synthetase -
  LIS81_RS18720 (LIS81_18735) truB 3670120..3671043 (-) 924 WP_002194816.1 tRNA pseudouridine(55) synthase TruB -
  LIS81_RS18725 (LIS81_18740) rbfA 3671130..3671486 (-) 357 WP_000776445.1 30S ribosome-binding factor RbfA -
  LIS81_RS18730 (LIS81_18745) - 3671502..3671783 (-) 282 WP_000582364.1 DUF503 family protein -
  LIS81_RS18735 (LIS81_18750) infB 3671780..3673840 (-) 2061 WP_000036341.1 translation initiation factor IF-2 -
  LIS81_RS18740 (LIS81_18755) - 3673845..3674156 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  LIS81_RS18745 (LIS81_18760) - 3674157..3674429 (-) 273 WP_000071128.1 YlxR family protein -
  LIS81_RS18750 (LIS81_18765) nusA 3674441..3675547 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  LIS81_RS18755 (LIS81_18770) rimP 3675565..3676035 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  LIS81_RS18760 (LIS81_18775) - 3676368..3680669 (-) 4302 WP_048550491.1 PolC-type DNA polymerase III -
  LIS81_RS18765 (LIS81_18780) - 3680794..3682494 (-) 1701 WP_000814307.1 proline--tRNA ligase -
  LIS81_RS18770 (LIS81_18785) rseP 3682604..3683860 (-) 1257 WP_001090249.1 RIP metalloprotease RseP -
  LIS81_RS18775 (LIS81_18790) dxr 3683877..3685019 (-) 1143 WP_000790362.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  LIS81_RS18780 (LIS81_18795) cdsA 3685043..3685834 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  LIS81_RS18785 (LIS81_18800) uppS 3685852..3686628 (-) 777 WP_226640240.1 isoprenyl transferase -
  LIS81_RS18790 (LIS81_18805) frr 3686714..3687271 (-) 558 WP_000531501.1 ribosome recycling factor -
  LIS81_RS18795 (LIS81_18810) pyrH 3687274..3687996 (-) 723 WP_000042663.1 UMP kinase -
  LIS81_RS18800 (LIS81_18815) tsf 3688063..3688950 (-) 888 WP_001018581.1 translation elongation factor Ts -
  LIS81_RS18805 (LIS81_18820) rpsB 3689054..3689755 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  LIS81_RS18810 (LIS81_18825) codY 3690106..3690885 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  LIS81_RS18815 (LIS81_18830) hslU 3690963..3692354 (-) 1392 WP_000550082.1 ATP-dependent protease ATPase subunit HslU -
  LIS81_RS18820 (LIS81_18835) hslV 3692377..3692919 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  LIS81_RS18825 (LIS81_18840) xerC 3692962..3693861 (-) 900 WP_226640238.1 tyrosine recombinase XerC -
  LIS81_RS18830 (LIS81_18845) trmFO 3693927..3695231 (-) 1305 WP_242276160.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  LIS81_RS18835 (LIS81_18850) topA 3695282..3697360 (-) 2079 WP_226640236.1 type I DNA topoisomerase -
  LIS81_RS18840 (LIS81_18855) dprA 3697505..3698374 (-) 870 WP_046198500.1 DNA-processing protein DprA -
  LIS81_RS18845 (LIS81_18860) sucD 3698462..3699364 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  LIS81_RS18850 (LIS81_18865) sucC 3699384..3700544 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  LIS81_RS18855 (LIS81_18870) rnhB 3700738..3701511 (-) 774 WP_001174717.1 ribonuclease HII -
  LIS81_RS18860 (LIS81_18875) ylqF 3701563..3702453 (-) 891 WP_000236700.1 ribosome biogenesis GTPase YlqF -
  LIS81_RS18865 (LIS81_18880) lepB 3702474..3703025 (-) 552 WP_000711857.1 signal peptidase I -
  LIS81_RS18870 (LIS81_18885) rplS 3703127..3703471 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  LIS81_RS18875 (LIS81_18890) trmD 3703618..3704352 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  LIS81_RS18880 (LIS81_18895) rimM 3704352..3704867 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  LIS81_RS18885 (LIS81_18900) - 3704988..3705215 (-) 228 WP_000737398.1 KH domain-containing protein -
  LIS81_RS18890 (LIS81_18905) rpsP 3705230..3705502 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  LIS81_RS18895 (LIS81_18910) ffh 3705603..3706952 (-) 1350 WP_000863461.1 signal recognition particle protein -
  LIS81_RS18900 (LIS81_18915) - 3706965..3707297 (-) 333 WP_000891062.1 putative DNA-binding protein -
  LIS81_RS18905 (LIS81_18920) ftsY 3707432..3708421 (-) 990 WP_226640235.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=617727 LIS81_RS18810 WP_000421288.1 3690106..3690885(-) (codY) [Bacillus tropicus strain CK18]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=617727 LIS81_RS18810 WP_000421288.1 3690106..3690885(-) (codY) [Bacillus tropicus strain CK18]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATTGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAATAGTGCTTACACAGCATTTCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATTGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCAGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459