Detailed information NTG0617102

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: NUU05_RS02790
• Genome accession: NZ_CP102538
• Coordinates: 510051..510836 (+)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain TH-4
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 505051..515836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS02760 (NUU05_02750)	pflA	505327..506127 (+)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-
NUU05_RS02765 (NUU05_02755)	-	506339..506713 (+)	375	WP_011681547.1	membrane protein	-
NUU05_RS02770 (NUU05_02760)	-	506774..506947 (+)	174	WP_011681546.1	hypothetical protein	-
NUU05_RS02775 (NUU05_02765)	-	507019..507593 (-)	575	Protein_485	IS30 family transposase	-
NUU05_RS02780 (NUU05_02770)	-	507770..508222 (-)	453	WP_002946987.1	universal stress protein	-
NUU05_RS02785 (NUU05_02775)	-	508577..509791 (+)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
NUU05_RS02790 (NUU05_02780)	codY	510051..510836 (+)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
NUU05_RS02795 (NUU05_02785)	-	510899..511450 (+)	552	WP_002946999.1	cysteine hydrolase family protein	-
NUU05_RS02800 (NUU05_02790)	-	511574..512422 (+)	849	WP_011681545.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
NUU05_RS02805 (NUU05_02795)	msrA	512434..512943 (+)	510	WP_041827768.1	peptide-methionine (S)-S-oxide reductase MsrA	-
NUU05_RS02810 (NUU05_02800)	-	513096..514537 (+)	1442	Protein_492	6-phospho-beta-glucosidase	-
NUU05_RS02815 (NUU05_02805)	-	514864..515136 (+)	273	WP_224103183.1	glycosyltransferase	-
NUU05_RS02820	-	515168..515329 (+)	162	WP_224103235.1	hypothetical protein	-
NUU05_RS02825 (NUU05_02810)	gatC	515469..515771 (+)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=617102 NUU05_RS02790 WP_002951720.1 510051..510836(+) (codY) [Streptococcus thermophilus strain TH-4]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=617102 NUU05_RS02790 WP_002951720.1 510051..510836(+) (codY) [Streptococcus thermophilus strain TH-4]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502