Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EKM74_RS15425 Genome accession   NZ_AP019306
Coordinates   2898396..2899169 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain TUM9463     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2893396..2904169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS15405 trmFO 2893739..2895046 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  EKM74_RS15410 xerC 2895464..2896360 (+) 897 WP_001015601.1 tyrosine recombinase XerC -
  EKM74_RS15415 hslV 2896357..2896902 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  EKM74_RS15420 hslU 2896968..2898371 (+) 1404 WP_000379044.1 ATP-dependent protease ATPase subunit HslU -
  EKM74_RS15425 codY 2898396..2899169 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EKM74_RS15430 - 2899243..2899317 (+) 75 WP_031761472.1 hypothetical protein -
  EKM74_RS15435 rpsB 2899516..2900283 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  EKM74_RS15440 - 2900317..2900430 (+) 114 WP_001789890.1 hypothetical protein -
  EKM74_RS15445 tsf 2900465..2901346 (+) 882 WP_000201392.1 translation elongation factor Ts -
  EKM74_RS15450 pyrH 2901483..2902205 (+) 723 WP_000057330.1 UMP kinase -
  EKM74_RS15455 frr 2902224..2902778 (+) 555 WP_001280006.1 ribosome recycling factor -
  EKM74_RS15460 - 2903151..2903921 (+) 771 WP_000473699.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=61660 EKM74_RS15425 WP_000055337.1 2898396..2899169(+) (codY) [Staphylococcus aureus strain TUM9463]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=61660 EKM74_RS15425 WP_000055337.1 2898396..2899169(+) (codY) [Staphylococcus aureus strain TUM9463]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment