Detailed information NTG0061595

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SCI_RS04800
• Genome accession: NC_022238
• Coordinates: 971077..971919 (-)
• Length: 280 a.a.
• NCBI ID: WP_020997792.1
• Uniprot ID: U2ZGW0
• Organism: Streptococcus constellatus subsp. pharyngis C1050
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 966077..976919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCI_RS04785 (SCI_0943)	trmFO	966798..968132 (-)	1335	WP_006267737.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SCI_RS04790 (SCI_0944)	-	968339..968836 (-)	498	WP_006267892.1	hypothetical protein	-
SCI_RS04795 (SCI_0945)	topA	968898..970991 (-)	2094	WP_148290513.1	type I DNA topoisomerase	-
SCI_RS04800 (SCI_0946)	dprA/cilB/dalA	971077..971919 (-)	843	WP_020997792.1	DNA-processing protein DprA	Machinery gene
SCI_RS04805 (SCI_0947)	-	972004..972561 (-)	558	WP_006267839.1	sugar O-acetyltransferase	-
SCI_RS10250	-	972627..972840 (-)	214	Protein_950	CAT RNA binding domain-containing protein	-
SCI_RS04810 (SCI_0948)	-	972837..973619 (-)	783	WP_006267744.1	ribonuclease HII	-
SCI_RS04815 (SCI_0949)	ylqF	973606..974457 (-)	852	WP_006267825.1	ribosome biogenesis GTPase YlqF	-
SCI_RS04820 (SCI_0950)	-	974576..975493 (-)	918	WP_003069057.1	MBL fold metallo-hydrolase	-
SCI_RS04825 (SCI_0951)	-	975497..976609 (-)	1113	Protein_954	acyl-CoA dehydrogenase family protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31165.75 Da
• Isoelectric Point: 5.4273

>NTDB_id=61595 SCI_RS04800 WP_020997792.1 971077..971919(-) (dprA/cilB/dalA) [Streptococcus constellatus subsp. pharyngis C1050]
MDNFDIYKLKTAGLTNQQVINVLEYAEIREKELSVKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILEDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGSEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCIASGADVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=61595 SCI_RS04800 WP_020997792.1 971077..971919(-) (dprA/cilB/dalA) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGATAATTTTGATATTTATAAACTAAAAACAGCTGGTTTGACCAACCAACAAGTCATCAATGTATTGGAATACGCAGA
AATTCGCGAAAAAGAATTGTCAGTCAAAGATATGGCAGTTGTCTCCGAATGTCGTAATCCTGCTCTTTTTATTGAAAAAT
ATTTACAATTAGATGATGATTTATTACGTCAAGAATTTGAGAAATTCCCATCTTTTTCTATCTTGGAAGATGTATATCCT
TGGGATTTGAGTGAAATTTATAATCCACCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
AGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCCGTTCAAAAGATTATTAAAGAGCTAAACAATGAAT
TGGTTATCGTGAGTGGTTTAGCACGCGGAATTGATACCTCAGCTCACATGGCAGCATTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGTCTAGACGTTTTTTATCCAAGGGCAAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAATATGGTTCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GCAGAGGGGTTATTGTTGCTGAAGCAAAAATGCGCTCAGGCAGCCTTATTACTTGTGAGCGAGCAATGGAAGAAGGGCGA
GATGTATTTGCTATTCCAGGGTCAATTTTAGATGGAAGAAGTGATGGCTGTCATCATTTGATTCAGGAAGGAGCAAAATG
CATCGCATCAGGGGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

3D structure

• AlphaFold DB: U2ZGW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	75.714	100	0.757
dprA/cilB/dalA	Streptococcus pneumoniae D39	75.714	100	0.757
dprA/cilB/dalA	Streptococcus pneumoniae R6	75.714	100	0.757
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	75.714	100	0.757
dprA/cilB/dalA	Streptococcus mitis SK321	75.357	100	0.754
dprA	Streptococcus mutans UA159	65	100	0.65
dprA	Lactococcus lactis subsp. cremoris KW2	56.786	100	0.568
dprA	Legionella pneumophila strain ERS1305867	43.154	86.071	0.371
dprA	Staphylococcus aureus N315	36.879	100	0.371