Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SCI_RS03390 Genome accession   NC_022238
Coordinates   679938..680789 (+) Length   283 a.a.
NCBI ID   WP_006267466.1    Uniprot ID   F9P5B5
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 674938..685789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS03365 (SCI_0667) - 675160..676038 (+) 879 WP_003069751.1 F0F1 ATP synthase subunit gamma -
  SCI_RS03370 (SCI_0668) atpD 676073..677479 (+) 1407 WP_003025268.1 F0F1 ATP synthase subunit beta -
  SCI_RS03375 (SCI_0669) - 677490..677909 (+) 420 WP_003069748.1 F0F1 ATP synthase subunit epsilon -
  SCI_RS10210 (SCI_0670) - 678013..678243 (+) 231 WP_080564559.1 DUF1146 family protein -
  SCI_RS03380 (SCI_0671) murA 678281..679561 (+) 1281 WP_003069745.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SCI_RS03385 (SCI_0672) - 679554..679730 (+) 177 WP_003069742.1 DNA-directed RNA polymerase subunit beta -
  SCI_RS03390 (SCI_0673) endA 679938..680789 (+) 852 WP_006267466.1 DNA/RNA non-specific endonuclease Machinery gene
  SCI_RS03395 (SCI_0674) - 680943..682679 (+) 1737 WP_020997716.1 ABC transporter ATP-binding protein -
  SCI_RS03400 (SCI_0675) - 682689..684458 (+) 1770 WP_020999327.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 283 a.a.        Molecular weight: 31006.71 Da        Isoelectric Point: 10.3734

>NTDB_id=61593 SCI_RS03390 WP_006267466.1 679938..680789(+) (endA) [Streptococcus constellatus subsp. pharyngis C1050]
MARKKSNQKVAQSVAGVFLALVLALGGYSFSNYHNHSSTKHSDSTAINRSIRKNYAAPSQELAQSVLTESVKQQLKGKIE
WNGAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGE
YHHAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANASHSTGQNFYETKVRKALDKNKRVRYRVTLIYASEQD
LVPVGSHIEAKSSDGSLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 852 bp        

>NTDB_id=61593 SCI_RS03390 WP_006267466.1 679938..680789(+) (endA) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGCGAGAAAGAAATCCAACCAGAAAGTAGCGCAAAGTGTAGCAGGCGTATTTCTTGCACTTGTTCTTGCGCTGGGAGG
TTATTCTTTTAGCAATTATCATAATCATAGCAGTACGAAGCATTCTGACAGCACTGCTATTAACAGGAGTATTCGTAAGA
ATTATGCAGCACCCAGTCAAGAATTAGCACAGAGCGTTTTAACAGAATCCGTCAAACAACAGCTCAAAGGGAAAATCGAG
TGGAATGGCGCAGGGGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGAAGTATTCCTTATGCGGA
TAATAAGACAAAATTGGTCAGAGGCCGAACTGTTCCAACGGTAGCAAATGCTCTTTTGTCCAAAGCTACTCGTCAGTATA
GGAATCGTGAAGAAACAGGTAATGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCGGGTGAA
TATCATCATGCAGTTGACCGTGGACATCTGCTAGGTTATGCCTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACTAG
CAATCCTAAAAATATTGCGGTGCAAACGGCTTGGGCGAATCAAGCAAATGCTAGCCATTCTACAGGTCAAAATTTTTATG
AAACGAAAGTACGTAAAGCTCTTGATAAAAATAAACGAGTTCGGTATCGAGTGACCTTGATTTACGCAAGTGAGCAGGAT
TTAGTACCGGTTGGTTCACATATTGAAGCCAAGTCTAGCGACGGTAGTTTGGAAATAAATGTCTTTGTGCCAAACGTACA
GACAGGAATTCGATTAAATTATCAGACAGGAGAAGTGACGGTCACCAACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(114-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P5B5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

78.761

79.859

0.629
  endA Streptococcus pneumoniae D39

78.761

79.859

0.629
  endA Streptococcus pneumoniae R6

78.761

79.859

0.629
  endA Streptococcus pneumoniae TIGR4

78.761

79.859

0.629

Multiple sequence alignment