Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   LIO33_RS04965 Genome accession   NZ_CP085088
Coordinates   996426..997265 (-) Length   279 a.a.
NCBI ID   WP_012028260.1    Uniprot ID   A0A2K1T148
Organism   Streptococcus suis strain Ssuis_MA1     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 991426..1002265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO33_RS04950 uidA 991787..993586 (-) 1800 WP_012775174.1 beta-glucuronidase -
  LIO33_RS04955 - 993602..994630 (-) 1029 WP_012775175.1 sugar kinase -
  LIO33_RS04960 - 994686..996239 (-) 1554 WP_012775176.1 MFS transporter -
  LIO33_RS04965 endA 996426..997265 (-) 840 WP_012028260.1 DNA/RNA non-specific endonuclease Machinery gene
  LIO33_RS04970 - 997295..997486 (-) 192 WP_012775177.1 DNA-directed RNA polymerase subunit beta -
  LIO33_RS04975 murA 997479..998762 (-) 1284 WP_043028909.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  LIO33_RS04980 - 998786..999010 (-) 225 WP_012775178.1 DUF1146 family protein -
  LIO33_RS04985 - 999070..999486 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  LIO33_RS04990 atpD 999496..1000902 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  LIO33_RS04995 - 1000922..1001800 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30190.37 Da        Isoelectric Point: 6.2370

>NTDB_id=615324 LIO33_RS04965 WP_012028260.1 996426..997265(-) (endA) [Streptococcus suis strain Ssuis_MA1]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPNQELASSVLTEDVKKQLGNSIEWNSA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=615324 LIO33_RS04965 WP_012028260.1 996426..997265(-) (endA) [Streptococcus suis strain Ssuis_MA1]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGTAGCAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAATCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGAAATTCGATTGAATGGAATAGTGCT
GGAGCGTTTATTATTAACGGGAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGTCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K1T148

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.492

84.588

0.588
  endA Streptococcus pneumoniae D39

69.492

84.588

0.588
  endA Streptococcus pneumoniae R6

69.492

84.588

0.588
  endA Streptococcus pneumoniae TIGR4

69.492

84.588

0.588