Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SCRE_RS02105 Genome accession   NC_022236
Coordinates   408089..409972 (+) Length   627 a.a.
NCBI ID   WP_020997630.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 403089..414972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS02090 (SCRE_0412) fmt 405096..406031 (+) 936 WP_020997629.1 methionyl-tRNA formyltransferase -
  SCRE_RS02095 (SCRE_0413) rsmB 406021..407333 (+) 1313 Protein_390 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SCRE_RS02100 (SCRE_0414) - 407352..408092 (+) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SCRE_RS02105 (SCRE_0415) stkP 408089..409972 (+) 1884 WP_020997630.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SCRE_RS02110 (SCRE_0416) liaF 410235..410933 (+) 699 WP_020997631.1 cell wall-active antibiotics response protein LiaF -
  SCRE_RS02115 (SCRE_0417) - 410930..411925 (+) 996 WP_006267397.1 sensor histidine kinase -
  SCRE_RS02120 (SCRE_0418) - 411927..412559 (+) 633 WP_006267191.1 response regulator transcription factor -
  SCRE_RS02125 (SCRE_0419) - 412606..414006 (+) 1401 WP_020997632.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SCRE_RS02130 (SCRE_0420) - 414008..414400 (+) 393 WP_020997633.1 S1 RNA-binding domain-containing protein -
  SCRE_RS02135 (SCRE_0421) - 414520..414837 (-) 318 WP_006269734.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67999.20 Da        Isoelectric Point: 9.6707

>NTDB_id=61449 SCRE_RS02105 WP_020997630.1 408089..409972(+) (stkP) [Streptococcus constellatus subsp. pharyngis C232]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGTVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QPLENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLISASKPTTPTPIKETV
SSNSQPTTKPKTKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSD
SAKKDSVIRTNPQAGTQRREGSTVDLIVSKGPKTFTMEDYSGQKKADAINSLVQKYKVSKGLIKIEEVESSDYAAGTVVS
QTPAAGSTYDLTSKNRITLKVAKTVSSVTMPSYIGSTYEFAYNNLTEVIGVQGANVEKRIVTTAPAGTQAHTIIKQSPEA
KRPLNLKNDRIVLYVYEPKTEESSTSESSSQSGSSSNKNSPSSSSSSSSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=61449 SCRE_RS02105 WP_020997630.1 408089..409972(+) (stkP) [Streptococcus constellatus subsp. pharyngis C232]
ATGATTCAAGTCGGCAAGATATTTGCCGGGCGATATAGAATCATCAAACAAATTGGGCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTGAAAGTTCTAAGAACGAATTACCAGACGGATCCGATTG
CTGTGGCGCGCTTTCAAAGAGAGGCGCGAGCGATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGATATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAGTATGTGGCTGGGCTTGACTTAAAACGCTATATTAAAGAGCATGCTCC
TTTATCTAATGAAGAAGCGGTTCGGATTATGGGACAAATTCTTTTGGCAATGCGTTTGGCGCATACGCATGGAATTGTTC
ATCGTGATTTGAAGCCACAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCTGAAACGAGCCTGACGCAAACAAATTCAATGCTGGGAACTGTGCATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAAAGCGATATTTACGCTATGGGGATCATTTTCTATGAAATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCTGTCACAATTGCTTTGCAACATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTGCCA
CAGCCTCTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCCGCAGATCGCCGAAATGAGAAAAAGTTGGTTTTTGATGATACTGCCAAAGCAGATACCA
AGACGCTTCCTAAAGTGTCACAAAATACCTTAATTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAACAGTC
AGTAGTAATTCTCAACCCACAACCAAGCCAAAAACAAAGAAAAAACGTCGTTTAAGAACGCGTTATAAAGTGTTGTTGTC
GGCAGTAGTCTTAGTTATTGCAGCTTTGGTGGCTTTAGTCTATTTGAGTCCCTCAAATGTAAAAATACCAGATGTTACTG
GAAAAACCGTTGCGCAAGCACGTTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAGAAAGACGAATACAGTGAT
TCTGCTAAGAAAGATTCTGTCATTCGTACGAATCCACAAGCGGGAACACAACGTCGCGAAGGAAGCACAGTAGATTTGAT
TGTCTCAAAAGGGCCGAAAACATTTACTATGGAAGATTATAGCGGTCAAAAAAAAGCAGATGCTATCAACAGTTTGGTGC
AAAAATACAAAGTTTCAAAGGGCTTGATTAAAATTGAAGAAGTAGAAAGTAGTGACTATGCAGCAGGAACTGTTGTTAGT
CAGACGCCTGCAGCAGGTAGTACGTATGATTTGACTTCAAAAAATCGGATTACGTTAAAAGTAGCGAAGACGGTTTCAAG
TGTTACAATGCCAAGTTATATAGGTTCCACTTATGAATTTGCCTATAATAACCTTACCGAAGTTATTGGCGTTCAAGGAG
CTAATGTTGAAAAACGAATAGTTACAACAGCTCCAGCAGGAACACAGGCACACACGATTATTAAACAAAGCCCAGAAGCA
AAGAGGCCTCTAAATTTAAAAAATGATCGTATTGTCTTATATGTATATGAGCCAAAAACTGAAGAATCATCTACATCTGA
AAGTAGTTCGCAATCTGGAAGCAGTTCAAATAAAAATAGTCCATCATCTAGTAGTTCGTCGAGTAGCGGTAACGATGGAT
CAAGTTCGAAAACACCAGACACAAGCGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(436-503)

PASTA domain (PASTA)

(508-576)

PASTA domain (PASTA)

(367-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.209

92.982

0.616
  stkP Streptococcus pneumoniae D39

65.866

92.982

0.612
  stkP Streptococcus pneumoniae R6

65.866

92.982

0.612
  stkP Streptococcus pneumoniae Rx1

65.695

92.982

0.611
  pknB Streptococcus mutans UA159

58.632

93.301

0.547
  stkP/pknB Streptococcus salivarius strain HSISS4

58.519

86.124

0.504

Multiple sequence alignment