Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   NPS16_RS08585 Genome accession   NZ_CP101986
Coordinates   1815964..1818294 (-) Length   776 a.a.
NCBI ID   WP_019317530.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1810964..1823294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS08560 (NPS16_08560) - 1811299..1811544 (-) 246 WP_002263367.1 hypothetical protein -
  NPS16_RS08565 (NPS16_08565) - 1811849..1812052 (+) 204 WP_002267523.1 hypothetical protein -
  NPS16_RS08570 (NPS16_08570) mutY 1813091..1814236 (+) 1146 WP_002265472.1 A/G-specific adenine glycosylase -
  NPS16_RS08575 (NPS16_08575) - 1814428..1815477 (-) 1050 WP_019317529.1 zinc-dependent alcohol dehydrogenase family protein -
  NPS16_RS08580 (NPS16_08580) trxA 1815575..1815889 (-) 315 WP_002263363.1 thioredoxin -
  NPS16_RS08585 (NPS16_08585) mutS/mutS2 1815964..1818294 (-) 2331 WP_019317530.1 endonuclease MutS2 Machinery gene
  NPS16_RS08590 (NPS16_08590) - 1818513..1819259 (-) 747 WP_024782615.1 CPBP family intramembrane glutamic endopeptidase -
  NPS16_RS08595 (NPS16_08595) - 1819663..1820208 (-) 546 WP_002263361.1 CvpA family protein -
  NPS16_RS08600 (NPS16_08600) - 1820205..1820510 (-) 306 WP_002263360.1 hypothetical protein -
  NPS16_RS08605 (NPS16_08605) rnhC 1820706..1821617 (+) 912 WP_002264187.1 ribonuclease HIII -
  NPS16_RS08610 (NPS16_08610) lepB 1821637..1822224 (+) 588 WP_002263358.1 signal peptidase I -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87663.93 Da        Isoelectric Point: 6.5195

>NTDB_id=613887 NPS16_RS08585 WP_019317530.1 1815964..1818294(-) (mutS/mutS2) [Streptococcus mutans strain COCC33-14]
MNTKILKALEFDKVKKQFAHFLQSEQGQMELNDLLPMTNQEKIERSFAEIADVAQIFQEYASFGFGHSQDISESLRRLEL
GADLNTQELLAVKRILQMSAELKDFYDNLENVDLQILDCLFEKIETFPDLQGSLQAINDGGFIEDFASPELTKIRHHIHQ
NEQQIRQILQEMLKKQGDLLAENLIASRSGRSVLPVKNTYRHRIAGVAHDISASGNTVYIEPRAVVNLNEEMTQARADER
HEMTRILHDLSDRLRSQTDIIGNNAWLLGHIDFVRGKYLYMRENQASLPSLTTDQTIRLLSVRHPLLSNPIANDLHFEHD
TTAILITGPNTGGKTIMLKTLGITQLMAQSGLPILADEGSKVAVFKDIFADIGDEQSIEQSLSTFSSHMTHIVEILQKAN
KDSLVLFDELGAGTDPQEGAALAMSILEHLRLSDIKTMITTHYPELKAYGIETEFIENASMEFDMVTLSPTYHFMQGVPG
RSNAFEIARRLGLSEIIVAEAENLTNTDSDVNKIIERLENQTIESRRRLDNIREVEQENLKFNRAVKKLYNEFSHAQDKE
LRKAKLKAQEIVDKALAESDFILKNLQDKAQLKPHEIIEAKGKLKQLAPEIELSKNKVLKKAKKKRAAKVGDDIIVSSYG
QRGTLTKRFKDGRWEAQVGLIKMTLQESEFDLVKSDKAQASQKRQAHLVKRTSQKAPSARLDLRGKRYEEAMQELDEFID
QALLNNMAQVDIIHGIGTGVIRDGVTKYLRRNKQVKEFGYAPQNAGGSGATIVTFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=613887 NPS16_RS08585 WP_019317530.1 1815964..1818294(-) (mutS/mutS2) [Streptococcus mutans strain COCC33-14]
ATGAATACAAAGATTTTAAAAGCCTTAGAATTTGATAAGGTTAAAAAGCAATTTGCTCATTTTTTGCAGAGTGAGCAAGG
GCAAATGGAATTAAACGATTTATTACCTATGACTAATCAGGAAAAAATTGAACGTTCTTTTGCCGAAATTGCAGATGTAG
CACAGATTTTTCAGGAATATGCTTCCTTTGGCTTTGGGCACAGTCAGGATATTTCAGAAAGTTTACGTCGTTTAGAATTA
GGAGCGGATCTCAATACTCAAGAGCTTTTGGCTGTCAAACGTATTTTGCAGATGTCAGCAGAGCTCAAGGACTTTTATGA
TAATTTAGAAAATGTTGATTTACAAATTTTGGATTGCTTATTTGAAAAGATTGAAACGTTTCCTGATTTGCAAGGGAGTT
TACAAGCCATCAATGATGGTGGCTTTATTGAAGATTTTGCTAGTCCTGAATTAACTAAAATTCGTCATCATATTCACCAA
AATGAACAACAAATTCGTCAAATTCTTCAGGAAATGTTGAAGAAACAAGGTGATTTATTGGCTGAAAACCTTATTGCCAG
TCGCAGTGGTCGCAGTGTTCTTCCAGTGAAAAATACTTATCGTCATCGTATTGCAGGTGTTGCTCATGATATTTCAGCTT
CAGGAAATACGGTTTACATTGAACCTCGAGCTGTTGTTAATTTAAATGAAGAGATGACTCAGGCGCGTGCAGACGAACGC
CATGAAATGACTCGCATTTTACATGATTTATCCGATAGGCTAAGATCACAAACAGATATTATTGGTAATAATGCTTGGTT
GCTTGGACATATTGATTTTGTTCGTGGGAAATACCTTTATATGAGAGAAAATCAAGCCAGTCTTCCTAGTTTAACAACGG
ATCAAACTATCCGTCTTTTGAGTGTACGTCATCCTCTGCTAAGCAATCCAATTGCCAATGATTTACATTTTGAACATGAT
ACAACAGCCATTTTAATTACAGGTCCTAATACGGGCGGTAAAACCATCATGTTAAAAACATTGGGAATAACGCAACTGAT
GGCTCAGTCAGGTCTTCCTATTTTGGCTGATGAGGGAAGTAAGGTTGCTGTTTTTAAAGACATCTTTGCAGACATTGGTG
ATGAACAGTCCATTGAGCAAAGTTTATCCACTTTTTCAAGTCATATGACACATATTGTCGAAATTCTGCAAAAGGCCAAT
AAAGACAGCTTAGTCCTTTTTGATGAACTTGGTGCTGGTACAGATCCACAAGAAGGGGCAGCCTTGGCCATGAGTATTCT
AGAACATTTACGCTTATCAGATATTAAAACAATGATTACCACCCATTATCCAGAGCTCAAGGCCTATGGTATCGAAACAG
AATTTATTGAAAATGCGAGTATGGAATTTGATATGGTGACGCTCAGCCCCACCTATCATTTTATGCAAGGAGTACCGGGA
CGATCCAATGCTTTTGAGATTGCACGTCGTTTAGGTTTGTCTGAAATTATTGTTGCAGAAGCGGAAAATTTGACGAATAC
GGATTCAGATGTTAATAAAATTATTGAACGTTTGGAAAATCAAACCATTGAAAGTCGCAGACGTTTGGATAATATTCGTG
AAGTGGAGCAGGAAAATCTCAAATTTAATCGAGCCGTCAAAAAACTTTATAATGAATTCTCACATGCACAAGACAAAGAG
TTGCGTAAGGCCAAACTAAAGGCTCAAGAGATTGTTGACAAGGCTCTTGCAGAGAGTGATTTTATTCTCAAAAATCTTCA
AGACAAAGCACAACTTAAGCCCCATGAAATTATTGAAGCTAAAGGCAAGCTCAAGCAGTTGGCTCCCGAGATAGAGCTTT
CGAAAAATAAGGTTCTTAAAAAAGCTAAGAAGAAACGTGCTGCGAAAGTTGGAGATGATATTATTGTCAGCAGTTATGGG
CAAAGAGGAACGCTTACTAAGCGCTTCAAAGATGGTCGTTGGGAAGCACAAGTAGGGCTGATCAAAATGACTTTACAAGA
GTCAGAGTTTGATTTAGTGAAATCAGACAAAGCCCAAGCATCGCAGAAAAGACAAGCTCACCTTGTCAAAAGGACTTCTC
AAAAGGCTCCTAGTGCTAGACTTGATTTACGTGGCAAGCGTTATGAAGAAGCGATGCAAGAATTAGATGAATTCATTGAT
CAGGCACTCTTGAACAATATGGCTCAGGTTGACATCATCCATGGTATCGGAACTGGTGTTATCCGTGATGGCGTAACTAA
ATATCTTCGCCGTAATAAGCAAGTTAAGGAGTTTGGCTATGCTCCTCAAAATGCAGGTGGCTCGGGCGCTACAATCGTGA
CTTTCAAATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

Smr domain (Smr)

(701-776)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.848

100

0.405