Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   NPS18_RS08700 Genome accession   NZ_CP101984
Coordinates   1761687..1764017 (-) Length   776 a.a.
NCBI ID   WP_002263362.1    Uniprot ID   Q8DSD1
Organism   Streptococcus mutans strain UA-159     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1756687..1769017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS08675 (NPS18_08675) - 1757028..1757273 (-) 246 WP_002263367.1 hypothetical protein -
  NPS18_RS08680 (NPS18_08680) - 1757578..1757781 (+) 204 WP_002263366.1 hypothetical protein -
  NPS18_RS08685 (NPS18_08685) mutY 1758818..1759963 (+) 1146 WP_002263365.1 A/G-specific adenine glycosylase -
  NPS18_RS08690 (NPS18_08690) - 1760151..1761200 (-) 1050 WP_002263364.1 zinc-dependent alcohol dehydrogenase family protein -
  NPS18_RS08695 (NPS18_08695) trxA 1761298..1761612 (-) 315 WP_002263363.1 thioredoxin -
  NPS18_RS08700 (NPS18_08700) mutS/mutS2 1761687..1764017 (-) 2331 WP_002263362.1 endonuclease MutS2 Machinery gene
  NPS18_RS08705 (NPS18_08705) - 1764086..1764631 (-) 546 WP_002263361.1 CvpA family protein -
  NPS18_RS08710 (NPS18_08710) - 1764628..1764933 (-) 306 WP_002263360.1 hypothetical protein -
  NPS18_RS08715 (NPS18_08715) rnhC 1765129..1766040 (+) 912 WP_002271343.1 ribonuclease HIII -
  NPS18_RS08720 (NPS18_08720) lepB 1766060..1766647 (+) 588 WP_002263358.1 signal peptidase I -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87764.13 Da        Isoelectric Point: 6.5929

>NTDB_id=613652 NPS18_RS08700 WP_002263362.1 1761687..1764017(-) (mutS/mutS2) [Streptococcus mutans strain UA-159]
MNTKILKALEFDKVKKQFTHFLQSEQGQMELNDLLPMTNQEKIERSFAEIADVAQIFQEYASFGFGHSQDISESLRRLEL
GADLNTQELLAVKRILQMSAELKDFYDNLENVDLQILDCLFEKIETFPDLQGSLQAINDGGFIEDFASPELTKIRHHIHQ
NEQQIRQILQEMLKKQGDLLAENLIASRSGRSVLPVKNTYRHRIAGVIHDISASGNTVYIEPRAVVNLNEEMTQARADER
HEMTRILHDLSDRLRSQTDIIGNNAWLLGHIDFVRGKYLYMRENQASLPSLTTDQTIRLLSVRHPLLSNPIANDLHFEHD
TTAILITGPNTGGKTIMLKTLGITQLMAQSGLPILADEGSKVAVFKDIFADIGDEQSIEQSLSTFSSHMTHIVEILQKAN
KDSLVLFDELGAGTDPQEGAALAMSILEHLRLSDIKTMITTHYPELKAYGIETEFIENASMEFDMVTLSPTYHFMQGVPG
RSNAFEIARRLGLSEIIVAEAENLTNTDSDVNKIIERLENQTIESRRRLDNIREVEQENLKFNRAVKKLYNEFSHAQDKE
LRKAKLKAQEIVDKALAESDFILKNLQDKAQLKPHEIIEAKGKLKKLVPEIELSKNKVLKKAKKKRAAKVGDDIIVSSYG
QRGTLTKRFKDGRWEAQVGLIKMTLQESEFDLVKSDKAQASQKRQAHLVKRTSQKAPSARLDLRGKRYEEAMQELDEFID
QALLNNMAQVDIIHGIGTGVIRDGVTKYLRRNKQVKEFGYAPQNAGGSGATIVTFK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=613652 NPS18_RS08700 WP_002263362.1 1761687..1764017(-) (mutS/mutS2) [Streptococcus mutans strain UA-159]
ATGAATACAAAGATTTTAAAAGCCTTAGAATTTGATAAGGTTAAAAAGCAATTTACTCATTTCTTGCAGAGTGAGCAAGG
GCAAATGGAATTAAACGATTTATTACCTATGACCAATCAGGAAAAAATTGAACGTTCTTTTGCTGAAATTGCAGATGTAG
CACAGATTTTTCAGGAGTATGCTTCCTTTGGCTTTGGGCACAGTCAGGATATTTCAGAAAGTTTACGTCGTTTAGAATTA
GGAGCGGATCTCAATACTCAAGAGCTTTTGGCTGTCAAACGTATTTTGCAGATGTCAGCAGAGCTCAAGGACTTTTATGA
TAATTTAGAAAATGTTGATTTGCAAATTTTGGATTGCTTATTTGAAAAGATTGAAACGTTTCCTGATTTGCAAGGGAGTT
TACAAGCCATCAATGATGGTGGCTTTATTGAAGATTTTGCTAGTCCTGAATTAACTAAAATTCGTCATCATATTCACCAA
AATGAACAACAAATTCGTCAAATTCTTCAAGAAATGTTGAAGAAACAAGGTGATTTATTGGCTGAAAACCTTATTGCCAG
TCGCAGTGGTCGCAGTGTTCTTCCAGTGAAAAATACTTATCGTCATCGTATTGCAGGTGTTATTCATGATATTTCAGCTT
CAGGAAATACGGTTTACATTGAACCTCGAGCTGTTGTTAATTTAAATGAAGAGATGACTCAGGCGCGTGCAGACGAACGC
CATGAAATGACTCGCATTTTACATGATTTATCCGATAGGCTAAGATCACAAACAGATATTATTGGTAATAATGCTTGGTT
GCTTGGGCATATTGATTTTGTTCGTGGGAAATACCTTTATATGAGAGAAAATCAAGCCAGTCTTCCTAGTTTAACAACGG
ATCAAACTATCCGTCTTTTGAGTGTACGTCATCCTCTGCTAAGTAATCCAATTGCCAATGATTTACATTTTGAACATGAT
ACAACAGCCATTTTAATTACAGGTCCTAATACGGGCGGTAAAACCATCATGTTAAAAACATTGGGAATAACACAACTGAT
GGCTCAGTCAGGTCTTCCTATTTTGGCTGATGAGGGAAGTAAGGTTGCTGTTTTTAAAGACATCTTTGCAGACATTGGTG
ATGAACAGTCCATTGAGCAAAGTTTATCCACTTTTTCAAGTCATATGACACATATTGTCGAAATTCTGCAAAAGGCCAAT
AAAGACAGCTTAGTCCTTTTTGATGAACTTGGTGCTGGTACGGATCCACAAGAAGGGGCAGCCTTGGCCATGAGTATTCT
GGAACATTTACGCTTATCAGATATTAAAACAATGATTACCACCCATTATCCAGAGCTCAAGGCCTATGGTATCGAAACAG
AATTTATTGAAAATGCGAGTATGGAATTTGATATGGTGACGCTCAGCCCCACCTATCATTTTATGCAAGGAGTACCGGGA
CGATCCAATGCTTTTGAGATTGCACGTCGTTTAGGTTTGTCTGAAATTATTGTTGCAGAAGCGGAAAATTTGACGAATAC
GGATTCAGATGTTAATAAAATTATCGAACGTTTGGAAAATCAAACCATTGAAAGTCGCAGACGTTTGGATAATATTCGTG
AAGTGGAGCAGGAAAATCTCAAATTTAATCGAGCCGTCAAAAAACTTTATAATGAATTCTCACATGCACAAGACAAAGAG
TTGCGTAAGGCCAAACTAAAGGCTCAAGAGATTGTTGACAAGGCTCTTGCAGAGAGTGATTTTATTCTCAAAAATCTTCA
AGACAAAGCACAACTTAAGCCCCATGAAATTATTGAAGCTAAAGGCAAGCTCAAGAAGTTGGTTCCCGAGATAGAGCTTT
CGAAAAATAAGGTTCTTAAAAAAGCTAAGAAGAAACGTGCTGCGAAAGTTGGAGATGATATTATTGTCAGCAGTTATGGG
CAAAGAGGAACGCTTACTAAGCGCTTCAAAGATGGTCGTTGGGAAGCACAAGTAGGGCTGATCAAAATGACTTTACAAGA
GTCAGAGTTTGATTTAGTGAAATCAGACAAAGCCCAAGCATCGCAGAAAAGACAAGCTCACCTTGTCAAAAGGACTTCTC
AAAAGGCTCCTAGTGCTAGACTTGATTTACGTGGCAAGCGTTATGAAGAAGCGATGCAAGAATTAGATGAATTCATTGAT
CAGGCACTCTTGAACAATATGGCTCAGGTTGACATCATCCATGGTATCGGAACTGGTGTTATCCGTGATGGCGTAACTAA
ATATCTTCGCCGTAATAAGCAAGTTAAGGAGTTTGGCTATGCTCCTCAAAATGCAGGTGGTTCGGGCGCTACAATCGTGA
CTTTCAAATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(630-669)

Smr domain (Smr)

(701-776)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DSD1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.848

100

0.405