Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   NPS18_RS08510 Genome accession   NZ_CP101984
Coordinates   1723142..1723927 (-) Length   261 a.a.
NCBI ID   WP_002263472.1    Uniprot ID   P59388
Organism   Streptococcus mutans strain UA-159     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1718142..1728927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS08490 (NPS18_08490) gatA 1718685..1720151 (-) 1467 WP_002263829.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  NPS18_RS08495 (NPS18_08495) gatC 1720151..1720453 (-) 303 WP_002263475.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  NPS18_RS08500 (NPS18_08500) aspS 1720580..1722331 (-) 1752 WP_002352359.1 aspartate--tRNA ligase -
  NPS18_RS08505 (NPS18_08505) - 1722589..1723140 (-) 552 WP_002263473.1 cysteine hydrolase family protein -
  NPS18_RS08510 (NPS18_08510) codY 1723142..1723927 (-) 786 WP_002263472.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  NPS18_RS08515 (NPS18_08515) - 1724036..1725250 (-) 1215 WP_002263471.1 pyridoxal phosphate-dependent aminotransferase -
  NPS18_RS08520 (NPS18_08520) - 1725427..1725963 (+) 537 WP_002263470.1 biotin transporter BioY -
  NPS18_RS08525 (NPS18_08525) - 1726061..1726510 (+) 450 WP_002263469.1 universal stress protein -
  NPS18_RS08530 (NPS18_08530) - 1726788..1728173 (-) 1386 WP_002263468.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28970.13 Da        Isoelectric Point: 4.5032

>NTDB_id=613645 NPS18_RS08510 WP_002263472.1 1723142..1723927(-) (codY) [Streptococcus mutans strain UA-159]
MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYV
KSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLN
LQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKDYS

Nucleotide


Download         Length: 786 bp        

>NTDB_id=613645 NPS18_RS08510 WP_002263472.1 1723142..1723927(-) (codY) [Streptococcus mutans strain UA-159]
ATGGCTAATTTATTATCGAAAACGCGACGTATTACATCCATTTTACAACGCTCGGTTGAGAGCCTTCAAAGTGATTTGCC
TTATAATACGATTGCAGATCAATTGGCTGAAATTATTGATTGTAATGCTTGTATTATTGATGGTAGTGGTATTATTCTCG
GCTATGCTATGAAGTATAAAACCAATACAGATCGTGTTGAAGAATTTTTCCAAGCTAAAAAATTACCTGATGATTATGTA
AAATCGGCCAGCCGTATTTATGATACAGAAGCCAATCTGTCGGTTGAAAATGATTTGACCATTTTTCCAATTGAATCAAA
AGATATCTATCCTGATGGCTTGACGACTATTGCTCCCATCTATGGCGGCGGTATGCGTCTTGGTTCTCTTATTATCTGGC
GTAATGATAAAGAATTCAATGATGACGATTTGATTCTAATTGAGATTTCTTCTACTGTTGTTGGAATTCAATTATTGAAC
TTGCAGACAGAAAATCTTGAAGAAACAATTCGTAAGCAGACTGCTATTAATATGGCGATTAATACCTTGTCTTATTCAGA
AATGAAGGCTGTCGCAGCTATTCTCAATGAATTAGATGGCAATGAAGGTCGCTTGACCGCATCGGTTATTGCTGATCGTA
TCGGTATTACACGTAGCGTGATTGTTAATGCTCTTAGAAAGTTAGAAAGTGCCGGTATTATTGAAAGTCGTTCCTTAGGT
ATGAAAGGTACTTATCTCAAAGTTATTAATGAAGGTATTTTTGATAAATTAAAGGACTATAGTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59388

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.37

98.467

0.644
  codY Bacillus subtilis subsp. subtilis str. 168

48.047

98.084

0.471