Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   LA387_RS09325 Genome accession   NZ_CP084377
Coordinates   1825151..1826086 (+) Length   311 a.a.
NCBI ID   WP_003133316.1    Uniprot ID   A0A1I4GTA7
Organism   Lactococcus garvieae strain Lg-Granada     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1822959..1840574 1825151..1826086 within 0


Gene organization within MGE regions


Location: 1822959..1840574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA387_RS09315 typA 1822959..1824800 (+) 1842 WP_003133313.1 translational GTPase TypA -
  LA387_RS09320 - 1824875..1825105 (+) 231 WP_003133314.1 DUF3165 family protein -
  LA387_RS09325 comYH 1825151..1826086 (+) 936 WP_003133316.1 class I SAM-dependent methyltransferase Machinery gene
  LA387_RS09330 - 1826171..1827364 (+) 1194 WP_003133318.1 acetate kinase -
  LA387_RS09335 - 1827483..1828676 (+) 1194 WP_003133320.1 acetate kinase -
  LA387_RS09340 pyrH 1828767..1829483 (+) 717 WP_003133322.1 UMP kinase -
  LA387_RS09345 frr 1829513..1830070 (+) 558 WP_003133324.1 ribosome recycling factor -
  LA387_RS09350 - 1830178..1831038 (+) 861 WP_003133325.1 CvfB family protein -
  LA387_RS09355 msrA 1831196..1831711 (+) 516 WP_003133327.1 peptide-methionine (S)-S-oxide reductase MsrA -
  LA387_RS09360 - 1831708..1831923 (+) 216 WP_003133330.1 YozE family protein -
  LA387_RS09365 - 1831940..1832311 (+) 372 WP_003133332.1 VOC family protein -
  LA387_RS09370 - 1832547..1832945 (+) 399 WP_017370630.1 hypothetical protein -
  LA387_RS09375 - 1832949..1834010 (+) 1062 WP_051005735.1 hypothetical protein -
  LA387_RS09380 - 1834287..1835009 (+) 723 WP_225666560.1 DUF1430 domain-containing protein -
  LA387_RS09385 - 1835016..1835171 (+) 156 WP_017370631.1 hypothetical protein -
  LA387_RS09390 - 1835435..1835836 (+) 402 WP_017370632.1 hypothetical protein -
  LA387_RS09395 - 1835843..1837903 (+) 2061 WP_003133337.1 DUF1430 domain-containing protein -
  LA387_RS09400 - 1837910..1838539 (+) 630 WP_003133338.1 ABC transporter ATP-binding protein -
  LA387_RS09405 rplK 1838667..1839092 (+) 426 WP_003133340.1 50S ribosomal protein L11 -
  LA387_RS09410 rplA 1839182..1839871 (+) 690 WP_003133341.1 50S ribosomal protein L1 -
  LA387_RS09415 - 1839986..1840342 (+) 357 WP_017370633.1 hypothetical protein -
  LA387_RS09420 - 1840347..1840574 (-) 228 WP_003133343.1 hypothetical protein -

Sequence

Protein


Download         Length: 311 a.a.        Molecular weight: 35124.17 Da        Isoelectric Point: 4.6693

>NTDB_id=610873 LA387_RS09325 WP_003133316.1 1825151..1826086(+) (comYH) [Lactococcus garvieae strain Lg-Granada]
MDIEKIEKAFGLVLENIMAIQAELLTDFYDAFVEQNAAYLGALEFASLTKENNDKVRSMNLTKSEWQKLFQFVLLQGSRV
APMQANHNLTPDSIGFIFNFIIEELHKERKIRVLEFGSGTGNLAETLLVHMQKEVDYVGFEVDDLLLDLSASMSEVMGTE
ASFLQIDAVKPQPLESVDVVMSDLPVGYYPDDDTARHFQVHDKSEHTYVHHLMIEQSFKYLKESGFALFLAPDNLLTSAQ
SEFLKAWIKEHAHVAAVITLPSSLFKGAGKSIYLLSKNQTNTPTFVYPLADLADRSILQEFMSEFVKNVKI

Nucleotide


Download         Length: 936 bp        

>NTDB_id=610873 LA387_RS09325 WP_003133316.1 1825151..1826086(+) (comYH) [Lactococcus garvieae strain Lg-Granada]
ATGGATATAGAGAAAATCGAAAAAGCCTTTGGATTGGTTCTTGAAAATATTATGGCAATTCAAGCGGAGCTCTTGACGGA
TTTTTATGATGCTTTTGTGGAACAAAATGCAGCTTACTTAGGCGCTTTAGAGTTTGCATCTCTGACGAAGGAAAATAATG
ATAAGGTTCGTTCAATGAACCTCACGAAAAGTGAGTGGCAAAAGCTGTTTCAATTTGTCTTGCTTCAAGGGTCACGTGTC
GCACCAATGCAAGCAAATCATAATTTAACACCAGATTCTATTGGGTTTATCTTTAATTTCATCATTGAAGAGTTGCACAA
AGAAAGAAAGATTCGTGTACTAGAATTTGGCTCAGGAACAGGGAATTTAGCGGAAACGCTCTTGGTTCATATGCAAAAAG
AAGTAGACTATGTTGGTTTTGAAGTAGATGACCTCTTGTTGGATTTGTCCGCTTCAATGTCCGAAGTCATGGGAACAGAA
GCAAGTTTTCTCCAAATTGACGCCGTGAAACCACAGCCCTTGGAGTCTGTAGATGTTGTGATGAGTGATCTCCCGGTTGG
TTATTATCCAGACGATGACACTGCTCGCCATTTTCAAGTGCATGACAAATCAGAACATACCTATGTGCACCACTTAATGA
TTGAGCAATCCTTTAAGTATCTGAAGGAGAGTGGTTTTGCGCTCTTCTTAGCTCCAGATAATCTTTTGACAAGTGCACAG
TCAGAATTTTTGAAGGCTTGGATTAAAGAACATGCACATGTTGCTGCAGTCATTACATTGCCTTCATCACTCTTTAAAGG
TGCAGGAAAATCGATTTATTTATTAAGTAAAAACCAAACAAATACACCAACTTTTGTTTACCCCTTGGCTGATTTAGCAG
ACCGTTCTATTTTGCAAGAATTTATGTCTGAGTTTGTGAAAAATGTCAAGATTTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(132-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4GTA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

49.677

99.678

0.495
  comYH Streptococcus mutans UA159

49.355

99.678

0.492