Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   NMK49_RS05740 Genome accession   NZ_CP101124
Coordinates   1188340..1189113 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1183340..1194113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK49_RS05720 trmFO 1183684..1184991 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  NMK49_RS05725 xerC 1185408..1186304 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  NMK49_RS05730 hslV 1186301..1186846 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  NMK49_RS05735 hslU 1186912..1188315 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  NMK49_RS05740 codY 1188340..1189113 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  NMK49_RS05745 - 1189164..1189256 (+) 93 WP_001790530.1 hypothetical protein -
  NMK49_RS05750 rpsB 1189455..1190222 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  NMK49_RS05755 - 1190256..1190369 (+) 114 WP_001789890.1 hypothetical protein -
  NMK49_RS05760 tsf 1190404..1191285 (+) 882 WP_000201387.1 translation elongation factor Ts -
  NMK49_RS05765 pyrH 1191422..1192144 (+) 723 WP_000057330.1 UMP kinase -
  NMK49_RS05770 frr 1192163..1192717 (+) 555 WP_001280006.1 ribosome recycling factor -
  NMK49_RS05775 - 1193090..1193860 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=608919 NMK49_RS05740 WP_000055337.1 1188340..1189113(+) (codY) [Staphylococcus aureus subsp. aureus RN4220]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=608919 NMK49_RS05740 WP_000055337.1 1188340..1189113(+) (codY) [Staphylococcus aureus subsp. aureus RN4220]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428