Detailed information NTG0605610

Bioinformatically predicted

Overview

• Name: proC
• Type: Machinery gene
• Locus tag: LAE74_RS06570
• Genome accession: NZ_CP083395
• Coordinates: 1241418..1242155 (-)
• Length: 245 a.a.
• NCBI ID: WP_002780246.1
• Uniprot ID: A0A5T1L8T6
• Organism: Campylobacter coli strain C203018
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1236418..1247155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LAE74_RS06530 (LAE74_06495)	-	1236531..1237292 (+)	762	WP_025431509.1	ATP-binding protein	-
LAE74_RS06535 (LAE74_06500)	-	1237289..1237972 (+)	684	WP_002791740.1	3-methyladenine DNA glycosylase	-
LAE74_RS06540 (LAE74_06505)	thiD	1237972..1238784 (+)	813	WP_002786353.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
LAE74_RS06545 (LAE74_06510)	thiE	1238774..1239406 (+)	633	WP_223375610.1	thiamine phosphate synthase	-
LAE74_RS06550 (LAE74_06515)	-	1239384..1240013 (+)	630	WP_002783358.1	uroporphyrinogen-III synthase	-
LAE74_RS06555 (LAE74_06520)	-	1240006..1240458 (-)	453	WP_002777117.1	hypothetical protein	-
LAE74_RS06560 (LAE74_06525)	-	1240455..1241123 (-)	669	WP_002790524.1	hypothetical protein	-
LAE74_RS06565 (LAE74_06530)	-	1241116..1241421 (-)	306	WP_002790525.1	hypothetical protein	-
LAE74_RS06570 (LAE74_06535)	proC	1241418..1242155 (-)	738	WP_002780246.1	pyrroline-5-carboxylate reductase	Machinery gene
LAE74_RS06575 (LAE74_06540)	fliW	1242155..1242544 (-)	390	WP_002777093.1	flagellar assembly protein FliW	-
LAE74_RS06580 (LAE74_06545)	-	1242708..1243355 (+)	648	WP_002780248.1	outer membrane protein assembly factor BamD	-
LAE74_RS06585 (LAE74_06550)	lon	1243371..1245746 (+)	2376	WP_223375609.1	endopeptidase La	-
LAE74_RS06590 (LAE74_06555)	rpsR	1245802..1246062 (-)	261	WP_002777087.1	30S ribosomal protein S18	-
LAE74_RS06595 (LAE74_06560)	-	1246073..1246621 (-)	549	WP_002777084.1	single-stranded DNA-binding protein	-
LAE74_RS06600 (LAE74_06565)	rpsF	1246630..1247007 (-)	378	WP_002777082.1	30S ribosomal protein S6	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 26797.20 Da
• Isoelectric Point: 9.3032

>NTDB_id=605610 LAE74_RS06570 WP_002780246.1 1241418..1242155(-) (proC) [Campylobacter coli strain C203018]
MKADLYILANGAMAQALAYGLKDSYNIYIVGRNLEKLQILEKEGFKTLLYKDFNIENKNIILAFKPYALESVAANLKGKA
KILISVLANTDFDKLKLIQAQNYARIMPNTAAKYKASTTPYVLKNSNFKDEVIEILNTFGKAYELNEEKQMNAAMAISGC
APAFLALVAESIANAGVYEGLSKELSLNLTRSLFKSAAALLENEHPAIIKENICSPAGVTIKGIKVLEQKGIRGTFFEAL
NASAT

Nucleotide

• Length: 738 bp

>NTDB_id=605610 LAE74_RS06570 WP_002780246.1 1241418..1242155(-) (proC) [Campylobacter coli strain C203018]
ATGAAAGCTGATTTATATATACTTGCTAATGGTGCGATGGCGCAAGCTTTGGCTTATGGATTAAAAGATTCTTATAATAT
CTATATAGTCGGTAGAAATTTAGAAAAGCTTCAAATTTTAGAAAAAGAAGGTTTTAAAACTTTACTCTATAAAGATTTTA
ATATAGAAAATAAAAATATTATCTTAGCTTTTAAACCTTATGCCTTAGAAAGTGTCGCAGCAAATTTAAAAGGCAAGGCA
AAAATTTTAATTTCAGTTTTAGCCAATACGGATTTTGATAAATTAAAACTTATCCAAGCCCAAAATTATGCAAGGATAAT
GCCAAATACAGCAGCTAAATATAAAGCTTCCACAACTCCTTATGTTTTAAAAAATTCAAATTTTAAAGATGAAGTCATAG
AAATTTTAAATACTTTTGGCAAGGCTTATGAGTTAAACGAAGAAAAACAAATGAATGCTGCGATGGCTATAAGCGGTTGC
GCTCCTGCTTTTTTAGCATTAGTAGCTGAAAGCATTGCTAATGCTGGCGTGTATGAAGGATTATCAAAAGAGCTGAGTTT
AAATCTCACTCGTTCGCTTTTTAAAAGTGCTGCAGCCTTGCTAGAAAACGAGCACCCAGCCATCATTAAGGAAAATATCT
GCTCGCCTGCAGGTGTTACCATAAAAGGGATTAAAGTATTAGAGCAAAAAGGTATCCGTGGGACTTTTTTTGAGGCTCTT
AATGCTAGTGCAACATGA

Domains

Predicted by InterproScan.

• NADP oxidoreductase coenzyme F420-dependent (F420_oxidored) (7-88)

• Pyrroline-5-carboxylate reductase dimerisation (P5CR_dimer) (148-244)

3D structure

• AlphaFold DB: A0A5T1L8T6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
proC	Campylobacter jejuni subsp. jejuni 81-176	80.833	97.959	0.792