Detailed information NTG0605476

Bioinformatically predicted

Overview

• Name: proC
• Type: Machinery gene
• Locus tag: LAE76_RS06285
• Genome accession: NZ_CP083377
• Coordinates: 1189543..1190280 (-)
• Length: 245 a.a.
• NCBI ID: WP_002780246.1
• Uniprot ID: A0A5T1L8T6
• Organism: Campylobacter coli strain C203110
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1184543..1195280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LAE76_RS06245 (LAE76_06215)	-	1184656..1185417 (+)	762	WP_025431509.1	ATP-binding protein	-
LAE76_RS06250 (LAE76_06220)	-	1185414..1186097 (+)	684	WP_002791740.1	3-methyladenine DNA glycosylase	-
LAE76_RS06255 (LAE76_06225)	thiD	1186097..1186909 (+)	813	WP_002786353.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
LAE76_RS06260 (LAE76_06230)	thiE	1186899..1187531 (+)	633	WP_223375610.1	thiamine phosphate synthase	-
LAE76_RS06265 (LAE76_06235)	-	1187509..1188138 (+)	630	WP_002783358.1	uroporphyrinogen-III synthase	-
LAE76_RS06270 (LAE76_06240)	-	1188131..1188583 (-)	453	WP_002777117.1	hypothetical protein	-
LAE76_RS06275 (LAE76_06245)	-	1188580..1189248 (-)	669	WP_002790524.1	hypothetical protein	-
LAE76_RS06280 (LAE76_06250)	-	1189241..1189546 (-)	306	WP_002790525.1	hypothetical protein	-
LAE76_RS06285 (LAE76_06255)	proC	1189543..1190280 (-)	738	WP_002780246.1	pyrroline-5-carboxylate reductase	Machinery gene
LAE76_RS06290 (LAE76_06260)	fliW	1190280..1190669 (-)	390	WP_002777093.1	flagellar assembly protein FliW	-
LAE76_RS06295 (LAE76_06265)	-	1190833..1191480 (+)	648	WP_002780248.1	outer membrane protein assembly factor BamD	-
LAE76_RS06300 (LAE76_06270)	lon	1191496..1193871 (+)	2376	WP_223375609.1	endopeptidase La	-
LAE76_RS06305 (LAE76_06275)	rpsR	1193927..1194187 (-)	261	WP_002777087.1	30S ribosomal protein S18	-
LAE76_RS06310 (LAE76_06280)	-	1194198..1194746 (-)	549	WP_002777084.1	single-stranded DNA-binding protein	-
LAE76_RS06315 (LAE76_06285)	rpsF	1194755..1195132 (-)	378	WP_002777082.1	30S ribosomal protein S6	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 26797.20 Da
• Isoelectric Point: 9.3032

>NTDB_id=605476 LAE76_RS06285 WP_002780246.1 1189543..1190280(-) (proC) [Campylobacter coli strain C203110]
MKADLYILANGAMAQALAYGLKDSYNIYIVGRNLEKLQILEKEGFKTLLYKDFNIENKNIILAFKPYALESVAANLKGKA
KILISVLANTDFDKLKLIQAQNYARIMPNTAAKYKASTTPYVLKNSNFKDEVIEILNTFGKAYELNEEKQMNAAMAISGC
APAFLALVAESIANAGVYEGLSKELSLNLTRSLFKSAAALLENEHPAIIKENICSPAGVTIKGIKVLEQKGIRGTFFEAL
NASAT

Nucleotide

• Length: 738 bp

>NTDB_id=605476 LAE76_RS06285 WP_002780246.1 1189543..1190280(-) (proC) [Campylobacter coli strain C203110]
ATGAAAGCTGATTTATATATACTTGCTAATGGTGCGATGGCGCAAGCTTTGGCTTATGGATTAAAAGATTCTTATAATAT
CTATATAGTCGGTAGAAATTTAGAAAAGCTTCAAATTTTAGAAAAAGAAGGTTTTAAAACTTTACTCTATAAAGATTTTA
ATATAGAAAATAAAAATATTATCTTAGCTTTTAAACCTTATGCCTTAGAAAGTGTCGCAGCAAATTTAAAAGGCAAGGCA
AAAATTTTAATTTCAGTTTTAGCCAATACGGATTTTGATAAATTAAAACTTATCCAAGCCCAAAATTATGCAAGGATAAT
GCCAAATACAGCAGCTAAATATAAAGCTTCCACAACTCCTTATGTTTTAAAAAATTCAAATTTTAAAGATGAAGTCATAG
AAATTTTAAATACTTTTGGCAAGGCTTATGAGTTAAACGAAGAAAAACAAATGAATGCTGCGATGGCTATAAGCGGTTGC
GCTCCTGCTTTTTTAGCATTAGTAGCTGAAAGCATTGCTAATGCTGGCGTGTATGAAGGATTATCAAAAGAGCTGAGTTT
AAATCTCACTCGTTCGCTTTTTAAAAGTGCTGCAGCCTTGCTAGAAAACGAGCACCCAGCCATCATTAAGGAAAATATCT
GCTCGCCTGCAGGTGTTACCATAAAAGGGATTAAAGTATTAGAGCAAAAAGGTATCCGTGGGACTTTTTTTGAGGCTCTT
AATGCTAGTGCAACATGA

Domains

Predicted by InterproScan.

• NADP oxidoreductase coenzyme F420-dependent (F420_oxidored) (7-88)

• Pyrroline-5-carboxylate reductase dimerisation (P5CR_dimer) (148-244)

3D structure

• AlphaFold DB: A0A5T1L8T6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
proC	Campylobacter jejuni subsp. jejuni 81-176	80.833	97.959	0.792