Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   M9H69_RS10020 Genome accession   NZ_CP097843
Coordinates   2001038..2002888 (-) Length   616 a.a.
NCBI ID   WP_250315544.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1996038..2007888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS10005 (M9H69_10005) - 1998698..1999504 (-) 807 WP_250315541.1 LPXTG cell wall anchor domain-containing protein -
  M9H69_RS10010 (M9H69_10010) - 1999521..2000594 (-) 1074 WP_250315542.1 hypothetical protein -
  M9H69_RS10015 (M9H69_10015) - 2000608..2000946 (-) 339 WP_250315543.1 conjugal transfer protein TrbC -
  M9H69_RS10020 (M9H69_10020) clpE 2001038..2002888 (-) 1851 WP_250315544.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  M9H69_RS10025 (M9H69_10025) - 2002891..2004636 (-) 1746 WP_250315545.1 DNA topoisomerase -

Sequence

Protein


Download         Length: 616 a.a.        Molecular weight: 69768.85 Da        Isoelectric Point: 5.4323

>NTDB_id=596663 M9H69_RS10020 WP_250315544.1 2001038..2002888(-) (clpE) [Streptococcus oralis strain HP01]
MTTEEKKKTPYLDRYTDNLTEKVSKKAEDYQVYGRDKEVEAVQTSLLRRTKNNPILVGEAGVGKTAIVEGFALAILRNQV
SPKLKNLTVRSLELSSLMSDEDGGFIVKFKKIIEEMVETKGENLLFIDEIHTIVGAGGSDKGALDAGNIIKPVLSRGEIQ
LIGATTLDEFHEYIETDRALERRMQPIMVSEPTTTQAIEILEQAKTIYEKFHQVSISSDAVKQAVLLSVRYIPDQFLPDK
AFDLIDEAATICSTNELAHVGKQEIAEVLKNKTGIPVTTILKGDKERLDGLKEKLSRRVKGQDEAVDAVVNAITVAQAGL
QDQRKPLSSFMFLGTSGVGKTELALALAEGMFDDEEAIIRFDMSEYKQKGDITKLIGDRQTRTKGQLTEKVKQKPYSVIL
IDEVEKAHSEVVDLFLQVLDAGRLTDSTGRQVSFKNTIIIITTNIGSQKIIKQYELKGNFKKLTDRDKVQFEKSMTLELE
TRFRPEFLNRIEYKLIFNMLDEEVNKEIIVKHLSEIEERMKNQRLTLSYEESLVTYLLDIGTNIKDGARPLERVIKHKVL
PLISKEFLNLSDHNQEYHFHLWVEGDSPDEHHREDKRKILFDVEAEKTSFGEALFS

Nucleotide


Download         Length: 1851 bp        

>NTDB_id=596663 M9H69_RS10020 WP_250315544.1 2001038..2002888(-) (clpE) [Streptococcus oralis strain HP01]
GTGACTACTGAAGAAAAGAAAAAAACACCCTATTTAGATCGTTATACAGATAATTTGACAGAAAAAGTTTCAAAAAAAGC
AGAAGATTATCAGGTGTACGGACGTGATAAAGAAGTAGAAGCTGTTCAGACCTCTCTTCTCAGGAGAACCAAGAACAATC
CAATTTTAGTGGGAGAAGCTGGAGTTGGTAAAACAGCCATTGTTGAAGGATTTGCTTTGGCCATTTTACGAAACCAGGTA
TCTCCAAAATTAAAAAACTTGACAGTGCGATCTTTGGAATTATCTAGTTTAATGTCAGATGAGGATGGAGGATTTATTGT
TAAGTTTAAAAAAATTATTGAGGAGATGGTAGAAACCAAAGGAGAAAACCTTCTCTTTATTGATGAAATTCATACAATTG
TTGGTGCTGGAGGTTCAGATAAAGGGGCTCTGGATGCTGGAAATATTATTAAGCCAGTTTTGTCACGTGGTGAGATTCAA
TTGATTGGCGCAACTACTTTAGATGAATTTCATGAATATATCGAAACGGACCGAGCGCTAGAGCGAAGGATGCAGCCAAT
TATGGTTTCTGAACCGACAACTACTCAAGCGATTGAAATTCTTGAACAAGCTAAAACTATTTATGAAAAATTTCACCAGG
TGTCTATTAGTTCCGACGCTGTAAAACAAGCTGTACTTCTATCTGTTCGCTACATACCAGATCAATTTTTACCTGATAAA
GCCTTCGACTTAATAGATGAAGCAGCGACAATTTGTTCTACAAATGAATTAGCCCATGTCGGGAAGCAAGAAATTGCAGA
GGTGCTGAAAAATAAAACAGGTATTCCTGTCACGACGATTTTGAAAGGTGACAAGGAAAGGCTAGATGGTTTAAAAGAAA
AGCTATCACGACGTGTTAAAGGCCAAGATGAGGCTGTAGATGCTGTTGTGAACGCTATAACTGTTGCACAAGCTGGTTTA
CAGGATCAAAGAAAGCCCCTATCTTCCTTCATGTTTCTAGGCACTTCAGGAGTTGGGAAAACAGAGCTTGCTTTGGCACT
AGCAGAGGGAATGTTTGATGATGAAGAGGCAATCATTCGTTTTGATATGTCTGAGTATAAGCAAAAAGGAGATATTACAA
AGCTGATTGGCGATCGTCAAACTAGAACGAAAGGTCAATTGACTGAGAAGGTTAAACAAAAACCTTATAGCGTTATCCTG
ATCGATGAAGTGGAGAAAGCACACTCAGAAGTTGTAGATTTATTTTTGCAGGTGCTTGATGCAGGACGTTTGACTGATTC
AACTGGAAGGCAAGTGAGTTTTAAGAATACGATTATTATTATTACTACGAATATTGGTTCTCAAAAAATTATTAAGCAGT
ACGAATTAAAAGGGAATTTTAAAAAGCTAACCGACAGGGATAAAGTTCAGTTTGAAAAGAGCATGACGTTGGAGTTAGAA
ACTAGGTTCAGACCAGAATTTCTCAATCGAATTGAATATAAATTGATTTTCAACATGTTAGACGAGGAAGTGAATAAGGA
AATTATTGTCAAACATCTATCAGAAATCGAAGAAAGAATGAAGAATCAAAGGTTGACTCTTTCTTATGAAGAAAGTTTGG
TTACTTATTTATTGGATATAGGAACAAATATAAAAGATGGTGCACGACCACTGGAAAGAGTGATTAAACATAAGGTTCTC
CCTTTAATTTCTAAAGAGTTTCTGAACTTATCTGATCACAACCAAGAGTATCATTTTCATCTTTGGGTAGAAGGTGATTC
GCCAGATGAACACCATCGTGAAGATAAAAGAAAAATATTATTCGATGTCGAAGCTGAAAAAACGTCATTTGGTGAAGCAT
TATTTTCTTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(325-492)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(500-569)

ATPase family associated with various cellular activities (AAA) (AAA)

(55-167)

AAA lid domain (AAA_lid_9)

(194-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

39.228

100

0.396
  clpC Lactococcus lactis subsp. cremoris KW2

38.315

100

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

38.278

100

0.39
  clpE Streptococcus pneumoniae R6

38.25

100

0.383
  clpE Streptococcus pneumoniae TIGR4

38.25

100

0.383
  clpE Streptococcus pneumoniae Rx1

38.25

100

0.383
  clpE Streptococcus pneumoniae D39

38.25

100

0.383
  clpC Streptococcus pneumoniae TIGR4

39.562

96.429

0.381
  clpC Streptococcus pneumoniae Rx1

39.562

96.429

0.381
  clpC Streptococcus pneumoniae D39

39.562

96.429

0.381
  clpC Streptococcus thermophilus LMD-9

38.704

97.727

0.378
  clpC Streptococcus thermophilus LMG 18311

38.538

97.727

0.377
  clpC Streptococcus mutans UA159

39.057

96.429

0.377