Detailed information NTG0594142

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: M3N36_RS08145
• Genome accession: NZ_CP097251
• Coordinates: 1594282..1596621 (-)
• Length: 779 a.a.
• NCBI ID: WP_023078038.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1589282..1601621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3N36_RS08105 (M3N36_08105)	rpsR	1589590..1589829 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
M3N36_RS08110 (M3N36_08110)	ssb	1589994..1590485 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
M3N36_RS08115 (M3N36_08115)	rpsF	1590507..1590797 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
M3N36_RS08120 (M3N36_08120)	-	1590970..1591263 (-)	294	WP_002983113.1	hypothetical protein	-
M3N36_RS08125 (M3N36_08125)	mutY	1591431..1592585 (+)	1155	WP_164972006.1	A/G-specific adenine glycosylase	-
M3N36_RS08130 (M3N36_08130)	-	1592762..1593337 (+)	576	WP_030127554.1	helix-turn-helix transcriptional regulator	-
M3N36_RS08135 (M3N36_08135)	trxA	1593383..1593715 (-)	333	WP_001932060.1	thioredoxin	-
M3N36_RS08140 (M3N36_08140)	-	1593778..1594278 (-)	501	WP_011018191.1	phosphatase PAP2 family protein	-
M3N36_RS08145 (M3N36_08145)	mutS/mutS2	1594282..1596621 (-)	2340	WP_023078038.1	endonuclease MutS2	Machinery gene
M3N36_RS08150 (M3N36_08150)	-	1596770..1597315 (-)	546	WP_002983087.1	CvpA family protein	-
M3N36_RS08155 (M3N36_08155)	-	1597318..1597626 (-)	309	WP_002993251.1	hypothetical protein	-
M3N36_RS08160 (M3N36_08160)	rnhC	1597783..1598685 (+)	903	WP_010922635.1	ribonuclease HIII	-
M3N36_RS08165 (M3N36_08165)	lepB	1598696..1599289 (+)	594	WP_030127555.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87850.07 Da
• Isoelectric Point: 6.5465

>NTDB_id=594142 M3N36_RS08145 WP_023078038.1 1594282..1596621(-) (mutS/mutS2) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=594142 M3N36_RS08145 WP_023078038.1 1594282..1596621(-) (mutS/mutS2) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTTAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAACTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAAAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATTACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCGCAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCCATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCCACATATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGTCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGCTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACATGATGAATTTACCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATCCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGCGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (324-505)

• Smr domain (Smr) (704-778)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-668)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.633	100	0.412