Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   M3M41_RS06035 Genome accession   NZ_CP097115
Coordinates   1222994..1223767 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain JP18270     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217994..1228767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3M41_RS06015 (M3M41_06010) trmFO 1218338..1219645 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  M3M41_RS06020 (M3M41_06015) xerC 1220062..1220958 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  M3M41_RS06025 (M3M41_06020) hslV 1220955..1221500 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  M3M41_RS06030 (M3M41_06025) hslU 1221566..1222969 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  M3M41_RS06035 (M3M41_06030) codY 1222994..1223767 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  M3M41_RS06040 (M3M41_06035) - 1223818..1223910 (+) 93 WP_001790530.1 hypothetical protein -
  M3M41_RS06045 (M3M41_06040) rpsB 1224109..1224876 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  M3M41_RS06050 (M3M41_06045) - 1224910..1225023 (+) 114 WP_001789890.1 hypothetical protein -
  M3M41_RS06055 (M3M41_06050) tsf 1225058..1225939 (+) 882 WP_000201387.1 translation elongation factor Ts -
  M3M41_RS06060 (M3M41_06055) pyrH 1226076..1226798 (+) 723 WP_000057330.1 UMP kinase -
  M3M41_RS06065 (M3M41_06060) frr 1226817..1227371 (+) 555 WP_001280006.1 ribosome recycling factor -
  M3M41_RS06070 (M3M41_06065) - 1227744..1228514 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=593538 M3M41_RS06035 WP_000055337.1 1222994..1223767(+) (codY) [Staphylococcus aureus strain JP18270]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=593538 M3M41_RS06035 WP_000055337.1 1222994..1223767(+) (codY) [Staphylococcus aureus strain JP18270]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428