Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | BSA_RS01115 | Genome accession | NC_021485 |
| Coordinates | 190858..191832 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008574.1 | Uniprot ID | A0AAV3JGK6 |
| Organism | Streptococcus agalactiae 09mas018883 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 191073..241642 | 190858..191832 | flank | -759 |
Gene organization within MGE regions
Location: 190858..241642
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BSA_RS01115 (BSA_2280) | comYH | 190858..191832 (+) | 975 | WP_001008574.1 | N-6 DNA methylase | Machinery gene |
| BSA_RS01120 (BSA_2290) | - | 191864..193057 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| BSA_RS01125 (BSA_2300) | - | 193209..193415 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| BSA_RS11575 (BSA_2310) | - | 193474..193611 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| BSA_RS01130 (BSA_2320) | - | 193652..194107 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| BSA_RS01135 (BSA_2330) | - | 194176..194841 (+) | 666 | WP_000008113.1 | type II CAAX endopeptidase family protein | - |
| BSA_RS01140 (BSA_2340) | proC | 194862..195632 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| BSA_RS01145 (BSA_2350) | pepA | 195702..196769 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| BSA_RS01150 (BSA_2360) | - | 196954..197193 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| BSA_RS01155 (BSA_2370) | - | 197354..197638 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| BSA_RS01160 (BSA_2380) | - | 197635..197958 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| BSA_RS01165 (BSA_2390) | ytpR | 197991..198617 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| BSA_RS01170 (BSA_2400) | - | 198671..199387 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| BSA_RS01175 (BSA_2410) | ssbA | 199468..199863 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| BSA_RS01180 (BSA_2420) | - | 199987..200631 (+) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| BSA_RS01185 (BSA_2430) | - | 200658..202403 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| BSA_RS01190 (BSA_2440) | - | 202384..203124 (+) | 741 | WP_000697630.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| BSA_RS01195 (BSA_2450) | - | 203294..203749 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| BSA_RS01200 (BSA_2460) | lrgB | 203751..204479 (+) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| BSA_RS01205 (BSA_2470) | - | 204722..206350 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| BSA_RS01210 (BSA_2480) | - | 206463..207440 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| BSA_RS01215 (BSA_2490) | - | 207437..208258 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| BSA_RS01220 (BSA_2500) | - | 208270..209073 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| BSA_RS01225 (BSA_2510) | - | 209057..209683 (+) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| BSA_RS01230 (BSA_2520) | treP | 209966..211996 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| BSA_RS01235 (BSA_2530) | treC | 212218..213843 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| BSA_RS01240 (BSA_2540) | - | 214059..216095 (+) | 2037 | WP_000228180.1 | BglG family transcription antiterminator | - |
| BSA_RS01245 (BSA_2550) | - | 216098..216382 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| BSA_RS01250 (BSA_2560) | - | 216395..217750 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| BSA_RS01255 (BSA_2570) | - | 217753..218610 (+) | 858 | WP_000203489.1 | transketolase | - |
| BSA_RS01260 (BSA_2580) | - | 218607..219536 (+) | 930 | WP_001203821.1 | transketolase C-terminal domain-containing protein | - |
| BSA_RS01265 (BSA_2590) | - | 219645..220904 (+) | 1260 | WP_001203071.1 | ferric reductase-like transmembrane domain-containing protein | - |
| BSA_RS01270 (BSA_2600) | rpsO | 220992..221261 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| BSA_RS01275 (BSA_2610) | pnp | 221642..223771 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| BSA_RS01280 (BSA_2620) | - | 223773..224525 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| BSA_RS01285 (BSA_2630) | cysE | 224534..225118 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| BSA_RS01290 (BSA_2640) | - | 225128..225310 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| BSA_RS01295 (BSA_2650) | cysS | 225307..226650 (+) | 1344 | WP_000591125.1 | cysteine--tRNA ligase | - |
| BSA_RS01300 (BSA_2660) | - | 226643..227029 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| BSA_RS01305 (BSA_2670) | rlmB | 227132..227887 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| BSA_RS01310 (BSA_2680) | - | 227884..228402 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| BSA_RS01315 (BSA_2690) | - | 228495..229355 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| BSA_RS11555 | - | 229892..230011 (+) | 120 | Protein_209 | helix-turn-helix domain-containing protein | - |
| BSA_RS01320 (BSA_2710) | rplM | 230236..230682 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| BSA_RS01325 (BSA_2720) | rpsI | 230703..231095 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| BSA_RS01330 (BSA_2730) | - | 231223..232377 (-) | 1155 | WP_000022165.1 | site-specific integrase | - |
| BSA_RS01335 (BSA_2740) | - | 232441..233031 (-) | 591 | WP_000181098.1 | helix-turn-helix transcriptional regulator | - |
| BSA_RS01340 (BSA_2750) | - | 233186..233491 (+) | 306 | WP_000331954.1 | hypothetical protein | - |
| BSA_RS01345 (BSA_2760) | - | 233627..233905 (+) | 279 | WP_000134670.1 | hypothetical protein | - |
| BSA_RS01350 (BSA_2770) | - | 233916..234146 (+) | 231 | WP_000360142.1 | hypothetical protein | - |
| BSA_RS01355 (BSA_2780) | - | 234159..234485 (+) | 327 | WP_000384270.1 | replication initiator protein A | - |
| BSA_RS01360 (BSA_2790) | - | 234489..235118 (+) | 630 | WP_000591148.1 | hypothetical protein | - |
| BSA_RS01365 (BSA_2800) | - | 235442..236317 (+) | 876 | WP_000770113.1 | hypothetical protein | - |
| BSA_RS01370 (BSA_2810) | - | 236353..236787 (+) | 435 | WP_001220479.1 | hypothetical protein | - |
| BSA_RS01375 (BSA_2820) | mobV | 237103..238359 (+) | 1257 | WP_000122832.1 | MobV family relaxase | - |
| BSA_RS01380 (BSA_2830) | - | 238527..238997 (+) | 471 | WP_000130119.1 | hypothetical protein | - |
| BSA_RS01385 (BSA_2840) | - | 239302..239637 (-) | 336 | WP_000384858.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BSA_RS01390 (BSA_2850) | - | 239627..239914 (-) | 288 | WP_000255538.1 | hypothetical protein | - |
| BSA_RS01395 (BSA_2860) | - | 240317..241537 (-) | 1221 | WP_000156558.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37046.02 Da Isoelectric Point: 4.5224
>NTDB_id=59051 BSA_RS01115 WP_001008574.1 190858..191832(+) (comYH) [Streptococcus agalactiae 09mas018883]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
Nucleotide
Download Length: 975 bp
>NTDB_id=59051 BSA_RS01115 WP_001008574.1 190858..191832(+) (comYH) [Streptococcus agalactiae 09mas018883]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
67.302 |
97.222 |
0.654 |
| comYH | Streptococcus mutans UA140 |
67.302 |
97.222 |
0.654 |