Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   KZB15_RS05405 Genome accession   NZ_CP079922
Coordinates   1107633..1108982 (-) Length   449 a.a.
NCBI ID   WP_000886210.1    Uniprot ID   A0A064BZM9
Organism   Streptococcus pneumoniae strain R36A     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1102633..1113982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZB15_RS05385 (KZB15_05395) - 1104287..1106158 (-) 1872 WP_000150986.1 Eco57I restriction-modification methylase domain-containing protein -
  KZB15_RS05390 (KZB15_05400) - 1106233..1106487 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  KZB15_RS05395 (KZB15_05405) relB 1106489..1106731 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  KZB15_RS05400 (KZB15_05410) vicX 1106822..1107631 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  KZB15_RS05405 (KZB15_05415) micB 1107633..1108982 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KZB15_RS05410 (KZB15_05420) micA 1108975..1109679 (-) 705 WP_000722076.1 response regulator YycF Regulator
  KZB15_RS05415 (KZB15_05425) mutY 1109734..1110909 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  KZB15_RS05420 (KZB15_05430) - 1111238..1112908 (-) 1671 WP_000845292.1 formate--tetrahydrofolate ligase -
  KZB15_RS05425 (KZB15_05435) coaB 1113138..1113827 (+) 690 WP_000699498.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51712.42 Da        Isoelectric Point: 4.9706

>NTDB_id=590113 KZB15_RS05405 WP_000886210.1 1107633..1108982(-) (micB) [Streptococcus pneumoniae strain R36A]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=590113 KZB15_RS05405 WP_000886210.1 1107633..1108982(-) (micB) [Streptococcus pneumoniae strain R36A]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACTAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGCTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064BZM9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.777

100

0.998
  vicK Streptococcus mutans UA159

69.9

89.532

0.626