Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AHML_RS20635 Genome accession   NC_021290
Coordinates   4616129..4617370 (+) Length   413 a.a.
NCBI ID   WP_016352169.1    Uniprot ID   -
Organism   Aeromonas hydrophila ML09-119     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4611129..4622370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AHML_RS23680 (AHML_20480) ampD 4611502..4612074 (-) 573 WP_016352163.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AHML_RS20610 (AHML_20485) - 4612222..4612692 (+) 471 WP_024944772.1 TIGR02281 family clan AA aspartic protease -
  AHML_RS20615 (AHML_20490) nadC 4612698..4613555 (+) 858 WP_016352165.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AHML_RS23685 (AHML_20500) tapA 4613878..4614300 (+) 423 WP_016352167.1 type IVa pilus major pilin TapA -
  AHML_RS20630 (AHML_20505) pilB 4614307..4616013 (+) 1707 WP_016352168.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  AHML_RS20635 (AHML_20510) pilC 4616129..4617370 (+) 1242 WP_016352169.1 type II secretion system F family protein Machinery gene
  AHML_RS20640 (AHML_20515) pilD 4617393..4618265 (+) 873 WP_016352170.1 A24 family peptidase Machinery gene
  AHML_RS20645 (AHML_20520) coaE 4618285..4618899 (+) 615 WP_016352171.1 dephospho-CoA kinase -
  AHML_RS20650 (AHML_20525) zapD 4618937..4619659 (+) 723 WP_016352172.1 cell division protein ZapD -
  AHML_RS20655 (AHML_20530) yacG 4619669..4619863 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  AHML_RS20660 (AHML_20535) mutT 4619924..4620337 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  AHML_RS20665 (AHML_20540) - 4620346..4621530 (-) 1185 WP_016352174.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45426.54 Da        Isoelectric Point: 9.8734

>NTDB_id=58887 AHML_RS20635 WP_016352169.1 4616129..4617370(+) (pilC) [Aeromonas hydrophila ML09-119]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQNWWYMIFGGVA
LAIFLYVRAWRASQKVRDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=58887 AHML_RS20635 WP_016352169.1 4616129..4617370(+) (pilC) [Aeromonas hydrophila ML09-119]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTAAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAGACCGGCACGCCTATGTCCGAGGCACTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCTCTGGAGACCATCTACGACCGCATC
GCCACCTATCGCGAAAAGTCCGAAGCCCTCAAATCCAAAATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTCACCTCCATTCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGACATCTTCAAGAGTTTCGGCGCCGAGC
TGCCCGCTTTTACCCAGTTCGTCATCGGTATCTCCCGCTTCATGCAGAACTGGTGGTATATGATCTTTGGCGGGGTTGCA
CTCGCCATCTTTCTCTATGTGCGCGCCTGGCGCGCCTCACAGAAAGTCAGAGACAACACCGACAAGTTCATACTAACCAT
CCCCGTGGTTGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGTACCCTCTCCACTACCTTCTCCGCCGGTA
TTCCACTGGTGGATGCCTTGGTCTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGCACTGCCGTCATGGCCATTCGT
AACGAGGTGGTGGCAGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGAGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCT
ATGTATCTACCCATCTTCAAACTGGGGTCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.576

95.884

0.552
  pilC Acinetobacter baumannii D1279779

54.25

96.852

0.525
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Vibrio cholerae strain A1552

47.99

96.368

0.462
  pilC Vibrio campbellii strain DS40M4

47.355

96.126

0.455
  pilG Neisseria meningitidis 44/76-A

40.494

98.063

0.397
  pilG Neisseria gonorrhoeae MS11

40.494

98.063

0.397
  pilC Thermus thermophilus HB27

38

96.852

0.368

Multiple sequence alignment