Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KU891_RS18245 Genome accession   NZ_CP078081
Coordinates   3591686..3592465 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus tropicus strain EMB20     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3565416..3611328 3591686..3592465 within 0


Gene organization within MGE regions


Location: 3565416..3611328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU891_RS18130 (KU891_18070) - 3565638..3566879 (-) 1242 WP_000592994.1 pitrilysin family protein -
  KU891_RS18135 (KU891_18075) - 3566966..3567865 (-) 900 WP_000647528.1 polysaccharide deacetylase family protein -
  KU891_RS18140 (KU891_18080) pnp 3568017..3570155 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  KU891_RS18145 (KU891_18085) rpsO 3570316..3570585 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  KU891_RS18150 (KU891_18090) ribF 3570686..3571657 (-) 972 WP_000766723.1 bifunctional riboflavin kinase/FAD synthetase -
  KU891_RS18155 (KU891_18095) truB 3571701..3572624 (-) 924 WP_000399340.1 tRNA pseudouridine(55) synthase TruB -
  KU891_RS18160 (KU891_18100) rbfA 3572711..3573067 (-) 357 WP_000776445.1 30S ribosome-binding factor RbfA -
  KU891_RS18165 (KU891_18105) - 3573083..3573364 (-) 282 WP_000582364.1 DUF503 family protein -
  KU891_RS18170 (KU891_18110) infB 3573361..3575421 (-) 2061 WP_000036344.1 translation initiation factor IF-2 -
  KU891_RS18175 (KU891_18115) - 3575426..3575737 (-) 312 WP_001286518.1 YlxQ family RNA-binding protein -
  KU891_RS18180 (KU891_18120) - 3575738..3576010 (-) 273 WP_000071128.1 YlxR family protein -
  KU891_RS18185 (KU891_18125) nusA 3576022..3577128 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  KU891_RS18190 (KU891_18130) rimP 3577146..3577616 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  KU891_RS18195 (KU891_18135) - 3577949..3582250 (-) 4302 WP_248139362.1 PolC-type DNA polymerase III -
  KU891_RS18200 (KU891_18140) - 3582375..3584075 (-) 1701 WP_000814307.1 proline--tRNA ligase -
  KU891_RS18205 (KU891_18145) rseP 3584185..3585441 (-) 1257 WP_001090249.1 RIP metalloprotease RseP -
  KU891_RS18210 (KU891_18150) dxr 3585458..3586600 (-) 1143 WP_071709105.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  KU891_RS18215 (KU891_18155) cdsA 3586624..3587415 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  KU891_RS18220 (KU891_18160) uppS 3587433..3588209 (-) 777 WP_000971301.1 isoprenyl transferase -
  KU891_RS18225 (KU891_18165) frr 3588295..3588852 (-) 558 WP_000531501.1 ribosome recycling factor -
  KU891_RS18230 (KU891_18170) pyrH 3588855..3589577 (-) 723 WP_000042663.1 UMP kinase -
  KU891_RS18235 (KU891_18175) tsf 3589644..3590531 (-) 888 WP_001018581.1 translation elongation factor Ts -
  KU891_RS18240 (KU891_18180) rpsB 3590635..3591336 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  KU891_RS18245 (KU891_18185) codY 3591686..3592465 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KU891_RS18250 (KU891_18190) hslU 3592543..3593934 (-) 1392 WP_000550082.1 ATP-dependent protease ATPase subunit HslU -
  KU891_RS18255 (KU891_18195) hslV 3593957..3594499 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  KU891_RS18260 (KU891_18200) xerC 3594542..3595441 (-) 900 WP_001101227.1 tyrosine recombinase XerC -
  KU891_RS18265 (KU891_18205) trmFO 3595507..3596811 (-) 1305 WP_003267294.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  KU891_RS18270 (KU891_18210) topA 3596862..3598940 (-) 2079 WP_001286966.1 type I DNA topoisomerase -
  KU891_RS18275 (KU891_18215) dprA 3599085..3599954 (-) 870 WP_071709106.1 DNA-processing protein DprA -
  KU891_RS18280 (KU891_18220) sucD 3600042..3600944 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  KU891_RS18285 (KU891_18225) sucC 3600964..3602124 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  KU891_RS18290 (KU891_18230) rnhB 3602318..3603091 (-) 774 WP_001174717.1 ribonuclease HII -
  KU891_RS18295 (KU891_18235) ylqF 3603143..3604033 (-) 891 WP_000236699.1 ribosome biogenesis GTPase YlqF -
  KU891_RS18300 (KU891_18240) lepB 3604054..3604605 (-) 552 WP_000711857.1 signal peptidase I -
  KU891_RS18305 (KU891_18245) rplS 3604707..3605051 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  KU891_RS18310 (KU891_18250) trmD 3605198..3605932 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  KU891_RS18315 (KU891_18255) rimM 3605932..3606447 (-) 516 WP_071709107.1 ribosome maturation factor RimM -
  KU891_RS18320 (KU891_18260) - 3606568..3606795 (-) 228 WP_000737398.1 KH domain-containing protein -
  KU891_RS18325 (KU891_18265) rpsP 3606810..3607082 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  KU891_RS18330 (KU891_18270) ffh 3607183..3608532 (-) 1350 WP_071709108.1 signal recognition particle protein -
  KU891_RS18335 (KU891_18275) - 3608545..3608877 (-) 333 WP_000891062.1 putative DNA-binding protein -
  KU891_RS18340 (KU891_18280) ftsY 3609012..3610001 (-) 990 WP_042989555.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=586606 KU891_RS18245 WP_000421288.1 3591686..3592465(-) (codY) [Bacillus tropicus strain EMB20]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=586606 KU891_RS18245 WP_000421288.1 3591686..3592465(-) (codY) [Bacillus tropicus strain EMB20]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATTGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAATAGTGCTTACACAGCATTTCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATTGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCAGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459