Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   KU525_RS11850 Genome accession   NZ_CP077920
Coordinates   2378492..2379562 (+) Length   356 a.a.
NCBI ID   WP_000776422.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 277     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2373492..2384562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU525_RS11820 (KU525_11855) - 2373915..2375378 (+) 1464 WP_001017865.1 rhomboid family protein -
  KU525_RS11825 (KU525_11860) - 2375359..2375562 (+) 204 WP_064626802.1 YqgQ family protein -
  KU525_RS11830 (KU525_11865) - 2375559..2376545 (+) 987 WP_225806189.1 ROK family glucokinase -
  KU525_RS11835 (KU525_11870) - 2376545..2376874 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  KU525_RS11840 (KU525_11875) - 2376871..2377494 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  KU525_RS11845 (KU525_11880) comGA 2377546..2378520 (+) 975 WP_000697217.1 competence type IV pilus ATPase ComGA Machinery gene
  KU525_RS11850 (KU525_11885) comGB 2378492..2379562 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  KU525_RS11855 (KU525_11890) comGC 2379576..2379887 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  KU525_RS11860 (KU525_11895) comGD 2379865..2380311 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  KU525_RS11865 (KU525_11900) comGE 2380298..2380597 (+) 300 WP_000844410.1 hypothetical protein Machinery gene
  KU525_RS11870 (KU525_11905) comGF 2380515..2381012 (+) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  KU525_RS11875 (KU525_11910) - 2381109..2381255 (+) 147 WP_001792109.1 hypothetical protein -
  KU525_RS11880 (KU525_11915) - 2381245..2381769 (+) 525 WP_001015120.1 shikimate kinase -
  KU525_RS11885 (KU525_11920) gcvT 2381928..2383019 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  KU525_RS11890 (KU525_11925) gcvPA 2383039..2384385 (+) 1347 WP_000019692.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41447.84 Da        Isoelectric Point: 10.0606

>NTDB_id=585135 KU525_RS11850 WP_000776422.1 2378492..2379562(+) (comGB) [Staphylococcus aureus strain 277]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=585135 KU525_RS11850 WP_000776422.1 2378492..2379562(+) (comGB) [Staphylococcus aureus strain 277]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGACTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATAAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGGGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

100

100

1
  comGB Staphylococcus aureus N315

100

100

1