Detailed information NTG0058441

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: I872_RS03060
• Genome accession: NC_021175
• Coordinates: 628586..629434 (+)
• Length: 282 a.a.
• NCBI ID: WP_015604694.1
• Uniprot ID: A0A512AB23
• Organism: Streptococcus cristatus AS 1.3089
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 623586..634434

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I872_RS03030 (I872_03020)	-	623758..624636 (+)	879	WP_015604689.1	F0F1 ATP synthase subunit gamma	-
I872_RS03035 (I872_03025)	atpD	624674..626080 (+)	1407	WP_005589740.1	F0F1 ATP synthase subunit beta	-
I872_RS03040 (I872_03030)	-	626088..626510 (+)	423	WP_095666415.1	F0F1 ATP synthase subunit epsilon	-
I872_RS03045 (I872_03035)	-	626752..626982 (+)	231	WP_041826785.1	DUF1146 family protein	-
I872_RS03050 (I872_03040)	murA	627051..628331 (+)	1281	WP_015604692.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
I872_RS03055 (I872_03045)	-	628324..628512 (+)	189	WP_015604693.1	DNA-directed RNA polymerase subunit beta	-
I872_RS03060 (I872_03050)	endA	628586..629434 (+)	849	WP_015604694.1	DNA/RNA non-specific endonuclease	Machinery gene
I872_RS03065 (I872_03055)	-	629642..630601 (+)	960	WP_015604695.1	ROK family glucokinase	-
I872_RS03070 (I872_03060)	-	630646..631053 (+)	408	WP_015604696.1	hypothetical protein	-
I872_RS03075 (I872_03065)	-	631137..631976 (+)	840	WP_015604697.1	thymidylate synthase	-
I872_RS03080 (I872_03070)	-	632112..632597 (+)	486	WP_015604698.1	hypothetical protein	-
I872_RS03085 (I872_03075)	-	632751..633263 (+)	513	WP_015604699.1	dihydrofolate reductase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 30590.18 Da
• Isoelectric Point: 10.0827

>NTDB_id=58441 I872_RS03060 WP_015604694.1 628586..629434(+) (endA) [Streptococcus cristatus AS 1.3089]
MPKRKKLQKKGTKSTQTVAGLLVALTLSLGAYFFGNANQSPSVNTPAVVSQNKDTSTPDQALAESVLTDSVRSQLGGKIE
WNRAGSFIINENQTNLDAKVSSVPYADNKTKMVQGQTVPTVANALLAKSTRQYKSREETGNGSTSWVPAGWHQVKHLSGE
YNHAVDRGHLLAYSLVGGLKGFDASTSNPANIAVQTAWANQANKDNSTGQNYYETQVRRALDQNKRVRYRVTLIYASEND
LVPSGSHLEAKSSDGSLEFNVFVPNVQSGIVLDYRTGKVTLI

Nucleotide

• Length: 849 bp

>NTDB_id=58441 I872_RS03060 WP_015604694.1 628586..629434(+) (endA) [Streptococcus cristatus AS 1.3089]
ATGCCAAAAAGAAAGAAATTACAAAAAAAGGGCACTAAATCTACTCAGACTGTAGCTGGTCTTCTGGTTGCTCTGACTTT
ATCACTGGGAGCCTACTTTTTTGGAAACGCCAATCAGTCACCATCAGTAAACACACCTGCAGTTGTCAGCCAAAATAAGG
ATACCAGTACACCAGATCAGGCATTGGCTGAGAGTGTTCTCACAGACTCAGTGCGTTCGCAACTTGGTGGAAAAATCGAG
TGGAATAGGGCTGGATCCTTCATTATCAATGAAAATCAAACAAACTTAGACGCTAAAGTTTCGAGTGTCCCTTATGCGGA
TAATAAAACGAAGATGGTTCAGGGACAGACGGTTCCAACAGTCGCCAATGCCTTGCTTGCCAAATCGACCCGCCAGTATA
AATCACGAGAAGAAACGGGAAATGGATCCACTTCTTGGGTTCCTGCCGGTTGGCACCAAGTCAAACATCTATCAGGTGAA
TACAACCATGCAGTAGATCGCGGGCATCTCTTGGCTTACTCTCTCGTCGGTGGCTTAAAGGGCTTTGATGCTTCCACTAG
CAATCCAGCCAATATCGCAGTCCAAACAGCCTGGGCCAATCAGGCCAATAAAGACAACTCGACGGGACAGAATTACTATG
AAACTCAAGTTCGTCGTGCTTTGGACCAGAATAAGCGAGTCCGCTATCGTGTCACTTTGATCTATGCTTCGGAAAATGAT
CTGGTGCCATCTGGCTCGCATTTAGAAGCCAAGTCCAGCGATGGAAGTTTGGAATTCAATGTCTTCGTTCCCAATGTCCA
GTCAGGAATTGTCCTTGATTATCGTACTGGCAAAGTGACCCTTATATAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (86-256)

3D structure

• AlphaFold DB: A0A512AB23

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.111	96.099	0.674
endA	Streptococcus pneumoniae D39	70.111	96.099	0.674
endA	Streptococcus pneumoniae R6	70.111	96.099	0.674
endA	Streptococcus pneumoniae TIGR4	70.111	96.099	0.674